EPH Receptor A5 antibody (AA 620-774)

Catalog No. ABIN969102

Product Details anti-EPH Receptor A5 Antibody

Target: EPH Receptor A5 (EPHA5)

Binding Specificity: AA 620-774

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This EPH Receptor A5 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Purification: purified

Immunogen: Purified recombinant fragment of EphA5 (aa620-774) expressed in E. coli.

Clone: 8B10B1

Isotype: IgG1

Application Details

Application Notes: ELISA: 1:10000, WB: 1:500 - 1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Ascitic fluid containing 0.03 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C/-20 °C

Storage Comment: 4°C, -20°C for long term storage

References for anti-EPH Receptor A5 antibody (ABIN969102)

Yang, Ramnath, Moysich, Asch, Swede, Alrawi, Huberman, Geradts, Brooks, Tan: "Prognostic significance of MCM2, Ki-67 and gelsolin in non-small cell lung cancer." in: BMC cancer, Vol. 6, pp. 203, (2006) (PubMed).

Wilkinson: "Multiple roles of EPH receptors and ephrins in neural development." in: Nature reviews. Neuroscience, Vol. 2, Issue 3, pp. 155-64, (2001) (PubMed).

Target Details for EPH Receptor A5

Target: EPH Receptor A5 (EPHA5)

Alternative Name: EphA5 (EPHA5 Products)

Background:

Description: EphA5: EPH receptor A5. This gene belongs to the ephrin receptor subfamily of the protein-tyrosine kinase family. EPH and EPH-related receptors have been implicated in mediating developmental events, particularly in the nervous system. Receptors in the EPH subfamily typically have a single kinase domain and an extracellular region containing a Cys-rich domain and 2 fibronectin type III repeats. The ephrin receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands.

Aliases: CEK7, EHK1, HEK7, TYRO4, EPHA5

Gene ID: 2044

HGNC: 2044

Pathways: RTK Signaling