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FGF2 antibody

FGF2 Reactivity: Human WB, ELISA, IHC Host: Mouse Monoclonal 2H5G2C11 unconjugated
Catalog No. ABIN969137
  • Target See all FGF2 Antibodies
    FGF2 (Fibroblast Growth Factor 2 (Basic) (FGF2))
    Reactivity
    • 127
    • 57
    • 54
    • 21
    • 17
    • 17
    • 5
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    Human
    Host
    • 116
    • 30
    • 3
    • 2
    Mouse
    Clonality
    • 112
    • 39
    Monoclonal
    Conjugate
    • 71
    • 15
    • 12
    • 9
    • 7
    • 5
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    This FGF2 antibody is un-conjugated
    Application
    • 106
    • 61
    • 50
    • 34
    • 26
    • 26
    • 20
    • 17
    • 16
    • 16
    • 11
    • 9
    • 7
    • 7
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
    Purification
    purified
    Immunogen
    Purified recombinant fragment of FGF2 expressed in E. coli.
    Clone
    2H5G2C11
    Top Product
    Discover our top product FGF2 Primary Antibody
  • Application Notes
    ELISA: 1:10000, WB: 1:500 - 1:2000, IHC: 1:200 - 1:1000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Ascitic fluid containing 0.03 % sodium azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C/-20 °C
    Storage Comment
    4°C, -20°C for long term storage
  • Kim, Shin, Choi, Kim, Ahn, Lee, Park, Kim, Mok, Nam: "A preliminary results of a randomized trial comparing monthly 5-flourouracil and cisplatin to weekly cisplatin alone combined with concurrent radiotherapy for locally advanced cervical cancer." in: Cancer research and treatment : official journal of Korean Cancer Association, Vol. 37, Issue 1, pp. 37-43, (2009) (PubMed).

    Romanov, James, Sherrington, Pettitt: "Basic fibroblast growth factor suppresses p53 activation in the neoplastic cells of a proportion of patients with chronic lymphocytic leukaemia." in: Oncogene, Vol. 24, Issue 45, pp. 6855-60, (2005) (PubMed).

    Webber, Chen, Hehr, Johnston, McFarlane: "Multiple signaling pathways regulate FGF-2-induced retinal ganglion cell neurite extension and growth cone guidance." in: Molecular and cellular neurosciences, Vol. 30, Issue 1, pp. 37-47, (2005) (PubMed).

  • Target
    FGF2 (Fibroblast Growth Factor 2 (Basic) (FGF2))
    Alternative Name
    FGF2 (FGF2 Products)
    Synonyms
    BFGF antibody, FGF-2 antibody, FGFB antibody, HBGF-2 antibody, Fgf-2 antibody, Fgfb antibody, bFGF antibody, fibroblast growth factor 2 antibody, fibroblast growth factor 2 (basic) antibody, FGF2 antibody, Fgf2 antibody, fgf2 antibody
    Background

    Description: FGF2 is a member of the fibroblast growth factor (FGF) family. FGF family members bind heparin and possess broad mitogenic and angiogenic activities. FGF2 is a single-chain polypeptide growth factor that plays a significant role in the process of wound healing and is a potent inducer of anguogenesis. Due to its basic pH , the factor is named FGF-2 (basic FGF, bFGF).Several different forms of the human protein exist ranging from 18-24 kDa in size due to the use of alternative start sites within the fgf-2 gene. It has a 55 percent amino acid residue identity to FIBROBLAST GROWTH FACTOR 1 and has potent heparin-binding activity. The growth factor is an extremely potent inducer of DNA synthesis in a variety of cell types from mesoderm and neuroectoderm lineages. It was originally named basic fibroblast growth factor based upon its chemical properties and to distinguish it from acidic fibroblast growth factor (FIBROBLAST GROWTH FACTOR 1).

    Aliases: BFGF, FGFB, HBGF-2, FGF2

    Gene ID
    2247
    HGNC
    2247
    Pathways
    RTK Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, C21-Steroid Hormone Metabolic Process, Inositol Metabolic Process, Glycosaminoglycan Metabolic Process, Protein targeting to Nucleus, S100 Proteins
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