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Fibulin 5 antibody

FBLN5 Reactivity: Human WB, ELISA Host: Mouse Monoclonal 3F8D5 unconjugated
Catalog No. ABIN969145
  • Target See all Fibulin 5 (FBLN5) Antibodies
    Fibulin 5 (FBLN5)
    Reactivity
    • 52
    • 30
    • 23
    • 1
    Human
    Host
    • 52
    • 5
    • 1
    Mouse
    Clonality
    • 53
    • 7
    Monoclonal
    Conjugate
    • 27
    • 8
    • 6
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This Fibulin 5 antibody is un-conjugated
    Application
    • 55
    • 31
    • 15
    • 5
    • 4
    • 3
    • 3
    • 1
    Western Blotting (WB), ELISA
    Purification
    purified
    Immunogen
    Purified recombinant fragment of Fibulin 5 expressed in E. coli.
    Clone
    3F8D5
    Isotype
    IgM
    Top Product
    Discover our top product FBLN5 Primary Antibody
  • Application Notes
    ELISA: 1:10000, WB: 1:500 - 1:2000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Ascitic fluid containing 0.03 % sodium azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C/-20 °C
    Storage Comment
    4°C, -20°C for long term storage
  • Wen, Hochholdinger, Sauer, Bruce, Schnable: "The roothairless1 gene of maize encodes a homolog of sec3, which is involved in polar exocytosis." in: Plant physiology, Vol. 138, Issue 3, pp. 1637-43, (2005) (PubMed).

    Kadoya, Sasaki, Kostka, Timpl, Matsuzaki, Kumagai, Sakai, Nishiyama, Amano: "Fibulin-5 deposition in human skin: decrease with ageing and ultraviolet B exposure and increase in solar elastosis." in: The British journal of dermatology, Vol. 153, Issue 3, pp. 607-12, (2005) (PubMed).

    Wang, LeMaire, Chen, Carter, Shen, Gan, Bartsch, Wilks, Utama, Ou, Thompson, Coselli, Wang: "Decreased expression of fibulin-5 correlates with reduced elastin in thoracic aortic dissection." in: Surgery, Vol. 138, Issue 2, pp. 352-9, (2005) (PubMed).

    Lee, Roy, Mogford, Schiemann, Mustoe: "Fibulin-5 promotes wound healing in vivo." in: Journal of the American College of Surgeons, Vol. 199, Issue 3, pp. 403-10, (2004) (PubMed).

  • Target
    Fibulin 5 (FBLN5)
    Alternative Name
    Fibulin 5 (FBLN5 Products)
    Synonyms
    zgc:103575 antibody, FBLN5 antibody, MGC108414 antibody, Fibulin-5 antibody, DKFZp469K0327 antibody, ADCL2 antibody, ARCL1A antibody, ARMD3 antibody, DANCE antibody, EVEC antibody, FIBL-5 antibody, UP50 antibody, A55 antibody, fibulin 5 antibody, fbln5 antibody, FBLN5 antibody, Fbln5 antibody
    Background

    Description: Fibulin 5(FBLN5), with 448-amino acid protein (about 50 kDa), is a recently discovered multifunctional extracellular matrix protein that mediates endothelial cell adhesion through integrin ligation, regulates cell growth and motility in a context-specific manner, and prevents elastinopathy in vivo. Fibulin-5 is abundantly expressed in great vessels and cardiac valves during embryogenesis, and in many adult tissues including the aorta, lung, uterus and skin, all of which contain abundant elastic fibres. Decreased fibulin-5 may contribute to the pathogenesis of aortic dissection by impairing elastic fiber assembly. Fibulin-5 is also a good marker of skin ageing and that the earlier loss of fibulin-5 may involve age-dependent changes in other elastic fibre components.

    Aliases: EVEC, UP50, ARMD3, DANCE

    Gene ID
    10516
    HGNC
    10516
    Pathways
    SARS-CoV-2 Protein Interactome
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