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GA Binding Protein Transcription Factor, alpha Subunit 60kDa (GABPA) (AA 120-190) antibody

Details for Product No. ABIN969163, Supplier: Log in to see
Antigen
  • gabpa-A
  • XrpFI
  • X-alpha1
  • GABPA
  • nft2
  • nrf2
  • nrf2a
  • e4tf1a
  • e4tf1-60
  • Nrf-2alpha
  • Nrf2a
  • E4TF1-60
  • E4TF1A
  • NFT2
  • NRF2
  • NRF2A
  • RCH04A07
  • GABPalpha
  • e4tf
  • wu:fc12d11
Epitope
AA 120-190
15
12
8
7
5
5
5
5
5
2
2
2
1
1
1
1
Reactivity
Human, Mouse (Murine)
84
22
16
2
2
1
1
1
Host
Mouse
50
34
Clonality (Clone)
Monoclonal ()
Conjugate
Un-conjugated
3
3
3
2
2
2
1
1
1
1
1
1
1
1
1
Application
Immunocytochemistry (ICC), ELISA, Western Blotting (WB)
65
35
27
13
11
4
4
3
2
2
1
1
Supplier
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Immunogen Purified recombinant fragment of human GABPA (AA 120-190) expressed in E. coli.
Clone 8C1B10
Isotype IgG1
Purification Ascites
Alternative Name GABPA (GABPA Antibody Abstract)
Background GABPA: GA binding protein transcription factor, alpha subunit 60 kDa. It is one of three GA-binding protein transcription factor subunits which functions as a DNA-binding subunit. Since this subunit shares identity with a subunit encoding the nuclear respiratory factor 2 gene, it is likely involved in activation of cytochrome oxidase expression and nuclear control of mitochondrial function. This subunit also shares identity with a subunit constituting the transcription factor E4TF1, responsible for expression of the adenovirus E4 gene. Because of its chromosomal localization and ability to form heterodimers with other polypeptides, it may play a role in the Down Syndrome phenotype.
Molecular Weight 51 kDa
Gene ID 2551
HGNC 2551
Research Area Chromatin and Nuclear Signaling, Transcription Factors
Application Notes Recommended Dilution:
ELISA: 1/10000, WB: 1/500 - 1/2000, ICC: 1/200 - 1/1000
Not yet tested in other applications.
Determining optimal working dilutions by titration test.
Restrictions For Research Use only
Format Liquid
Buffer Ascitic fluid containing 0.03 % sodium azide.
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment Store at 4 °C or at -20 °C for long term.
Supplier Images
Immunocytochemistry (ICC) image for anti-GA Binding Protein Transcription Factor, alpha Subunit 60kDa (GABPA) (AA 120-190) antibody (ABIN969163) Figure 1: Confocal immunofluorescence analysis of Hela cells using GABPA mouse mAb (g...
Western Blotting (WB) image for anti-GA Binding Protein Transcription Factor, alpha Subunit 60kDa (GABPA) (AA 120-190) antibody (ABIN969163) Figure 2: Western blot analysis using GABPA mouse mAb against Hela (1), A549 (2), MCF...
Western Blotting (WB) image for anti-GA Binding Protein Transcription Factor, alpha Subunit 60kDa (GABPA) (AA 120-190) antibody (ABIN969163) Figure 3: Western blot analysis using GABPA mouse mAb against HEK293T cells transfect...
Product cited in: Vogel, Kristie: "The novel coactivator C1 (HCF) coordinates multiprotein enhancer formation and mediates transcription activation by GABP." in: The EMBO journal, Vol. 19, Issue 4, pp. 683-90, 2000 (PubMed).

Sawada, Simizu, Suzuki et al.: "Synergistic transcriptional activation by hGABP and select members of the activation transcription factor/cAMP response element-binding protein family." in: The Journal of biological chemistry, Vol. 274, Issue 50, pp. 35475-82, 2000 (PubMed).

Background publications Batchelor, Piper, de la Brousse et al.: "The structure of GABPalpha/beta: an ETS domain- ankyrin repeat heterodimer bound to DNA." in: Science (New York, N.Y.), Vol. 279, Issue 5353, pp. 1037-41, 1998 (PubMed).