GA Binding Protein Transcription Factor, alpha Subunit 60kDa (GABPA) (AA 120-190) antibody

Details for Product No. ABIN969163, Supplier: Log in to see
Antigen
  • gabpa-A
  • XrpFI
  • X-alpha1
  • GABPA
  • nft2
  • nrf2
  • nrf2a
  • e4tf1a
  • e4tf1-60
  • Nrf-2alpha
  • Nrf2a
  • E4TF1-60
  • E4TF1A
  • NFT2
  • NRF2
  • NRF2A
  • RCH04A07
  • GABPalpha
  • e4tf
  • wu:fc12d11
  • GA binding protein transcription factor, alpha subunit 60kDa
  • GA binding protein transcription factor, alpha subunit
  • GA repeat binding protein, alpha
  • GA-binding protein transcription factor, alpha subunit
  • gabpa-A
  • GABPA
  • gabpa
  • LOC100222977
  • Gabpa
Alternatives
anti-Human GA Binding Protein Transcription Factor, alpha Subunit 60kDa antibody for Immunohistochemistry (Paraffin-embedded Sections)
Epitope
AA 120-190
12
10
9
8
8
8
6
5
5
5
3
2
2
1
1
1
1
1
1
1
Reactivity
Human, Mouse (Murine)
96
30
22
4
3
3
3
2
2
1
1
1
1
1
Host
Mouse
60
36
Clonality (Clone)
Monoclonal ()
Conjugate
Un-conjugated
3
3
3
2
2
2
1
1
1
1
1
1
1
1
1
1
1
Application
Immunocytochemistry (ICC), ELISA, Western Blotting (WB)
76
39
30
18
13
9
8
4
3
2
2
1
1
Options
Supplier
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Supplier Product No.
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Immunogen Purified recombinant fragment of human GABPA (aa120-190) expressed in E. Coli.
Clone 8C1B10
Isotype IgG1
Purification Ascites
Alternative Name GABPA (GABPA Antibody Abstract)
Background GABPA: GA binding protein transcription factor, alpha subunit 60 kDa. It is one of three GA-binding protein transcription factor subunits which functions as a DNA-binding subunit. Since this subunit shares identity with a subunit encoding the nuclear respiratory factor 2 gene, it is likely involved in activation of cytochrome oxidase expression and nuclear control of mitochondrial function. This subunit also shares identity with a subunit constituting the transcription factor E4TF1, responsible for expression of the adenovirus E4 gene. Because of its chromosomal localization and ability to form heterodimers with other polypeptides, it may play a role in the Down Syndrome phenotype.
Molecular Weight 51 kDa
Gene ID 2551
HGNC 2551
Research Area Chromatin and Nuclear Signaling, Transcription Factors
Pathways Myometrial Relaxation and Contraction
Application Notes ELISA: 1:10000, WB: 1:500 - 1:2000, ICC: 1:200 - 1:1000
Restrictions For Research Use only
Format Liquid
Buffer Ascitic fluid containing 0.03 % sodium azide.
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C,-20 °C
Storage Comment 4°C, -20°C for long term storage
Supplier Images
Immunocytochemistry (ICC) image for anti-GA Binding Protein Transcription Factor, alpha Subunit 60kDa (GABPA) (AA 120-190) antibody (ABIN969163) Figure 1: Confocal immunofluorescence analysis of Hela cells using GABPA mouse mAb (g...
Western Blotting (WB) image for anti-GA Binding Protein Transcription Factor, alpha Subunit 60kDa (GABPA) (AA 120-190) antibody (ABIN969163) Figure 2: Western blot analysis using GABPA mouse mAb against Hela (1), A549 (2), MCF...
Western Blotting (WB) image for anti-GA Binding Protein Transcription Factor, alpha Subunit 60kDa (GABPA) (AA 120-190) antibody (ABIN969163) Figure 3: Western blot analysis using GABPA mouse mAb against HEK293T cells transfect...
Product cited in: Sawada, Simizu, Suzuki, Sawa, Goto, Hasegawa, Imai, Watanabe, Handa: "Synergistic transcriptional activation by hGABP and select members of the activation transcription factor/cAMP response element-binding protein family." in: The Journal of biological chemistry, Vol. 274, Issue 50, pp. 35475-82, 2000 (PubMed).

Vogel, Kristie: "The novel coactivator C1 (HCF) coordinates multiprotein enhancer formation and mediates transcription activation by GABP." in: The EMBO journal, Vol. 19, Issue 4, pp. 683-90, 2000 (PubMed).

Background publications Batchelor, Piper, de la Brousse, McKnight, Wolberger: "The structure of GABPalpha/beta: an ETS domain- ankyrin repeat heterodimer bound to DNA." in: Science (New York, N.Y.), Vol. 279, Issue 5353, pp. 1037-41, 1998 (PubMed).

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