GABPA antibody (AA 120-190)

Catalog No. ABIN969163

Product Details anti-GABPA Antibody

Target: GABPA (GA Binding Protein Transcription Factor, alpha Subunit 60kDa (GABPA))

Binding Specificity: AA 120-190

Reactivity: Human, Mouse

Host: Mouse

Clonality: Monoclonal

Conjugate: This GABPA antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunocytochemistry (ICC)

Purification: purified

Immunogen: Purified recombinant fragment of human GABPA (aa120-190) expressed in E. coli.

Clone: 8C1B10

Isotype: IgG1

Application Details

Application Notes: ELISA: 1:10000, WB: 1:500 - 1:2000, ICC: 1:200 - 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Ascitic fluid containing 0.03 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C/-20 °C

Storage Comment: 4°C, -20°C for long term storage

References for anti-GABPA antibody (ABIN969163)

Sawada, Simizu, Suzuki, Sawa, Goto, Hasegawa, Imai, Watanabe, Handa: "Synergistic transcriptional activation by hGABP and select members of the activation transcription factor/cAMP response element-binding protein family." in: The Journal of biological chemistry, Vol. 274, Issue 50, pp. 35475-82, (2000) (PubMed).

Vogel, Kristie: "The novel coactivator C1 (HCF) coordinates multiprotein enhancer formation and mediates transcription activation by GABP." in: The EMBO journal, Vol. 19, Issue 4, pp. 683-90, (2000) (PubMed).

Target Details for GABPA

Target: GABPA (GA Binding Protein Transcription Factor, alpha Subunit 60kDa (GABPA))

Alternative Name: GABPA (GABPA Products)

Synonyms: gabpa-A antibody, XrpFI antibody, X-alpha1 antibody, GABPA antibody, nft2 antibody, nrf2 antibody, nrf2a antibody, e4tf1a antibody, e4tf1-60 antibody, Nrf-2alpha antibody, Nrf2a antibody, E4TF1-60 antibody, E4TF1A antibody, NFT2 antibody, NRF2 antibody, NRF2A antibody, RCH04A07 antibody, GABPalpha antibody, e4tf antibody, wu:fc12d11 antibody, GA binding protein transcription factor alpha subunit S homeolog antibody, GA binding protein transcription factor alpha subunit antibody, GA binding protein transcription factor, alpha subunit antibody, GA binding protein transcription factor alpha subunit L homeolog antibody, GA repeat binding protein, alpha antibody, gabpa.S antibody, GABPA antibody, gabpa antibody, Gabpa antibody, gabpa.L antibody

Background:

Description: GABPA: GA binding protein transcription factor, alpha subunit 60 kDa. It is one of three GA-binding protein transcription factor subunits which functions as a DNA-binding subunit. Since this subunit shares identity with a subunit encoding the nuclear respiratory factor 2 gene, it is likely involved in activation of cytochrome oxidase expression and nuclear control of mitochondrial function. This subunit also shares identity with a subunit constituting the transcription factor E4TF1, responsible for expression of the adenovirus E4 gene. Because of its chromosomal localization and ability to form heterodimers with other polypeptides, it may play a role in the Down Syndrome phenotype.

Aliases: NFT2, NRF2

Molecular Weight: 51 kDa

Gene ID: 2551

HGNC: 2551

Pathways: Myometrial Relaxation and Contraction