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HFE antibody

HFE Reactivity: Human WB, ELISA, ICC Host: Mouse Monoclonal 3F1 unconjugated
Catalog No. ABIN969192
  • Target See all HFE Antibodies
    HFE (Hemochromatosis (HFE))
    Reactivity
    • 47
    • 9
    • 8
    • 6
    • 6
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Human
    Host
    • 43
    • 5
    Mouse
    Clonality
    • 44
    • 4
    Monoclonal
    Conjugate
    • 25
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This HFE antibody is un-conjugated
    Application
    • 42
    • 20
    • 14
    • 13
    • 13
    • 6
    • 5
    • 3
    • 3
    • 2
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunocytochemistry (ICC)
    Purification
    purified
    Immunogen
    Purified recombinant fragment of human HFE expressed in E. coli.
    Clone
    3F1
    Isotype
    IgG1
    Top Product
    Discover our top product HFE Primary Antibody
  • Application Notes
    ELISA: 1:10000, WB: 1:500 - 1:2000, ICC: 1:200 - 1:1000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Ascitic fluid containing 0.03 % sodium azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C/-20 °C
    Storage Comment
    4°C, -20°C for long term storage
  • Hosgood, Menashe, He, Chanock, Lan: "PTEN identified as important risk factor of chronic obstructive pulmonary disease." in: Respiratory medicine, Vol. 103, Issue 12, pp. 1866-70, (2009) (PubMed).

    Valenti, Girelli, Valenti, Castagna, Como, Campostrini, Rametta, Dongiovanni, Messa, Fargion: "HFE mutations modulate the effect of iron on serum hepcidin-25 in chronic hemodialysis patients." in: Clinical journal of the American Society of Nephrology : CJASN, Vol. 4, Issue 8, pp. 1331-7, (2009) (PubMed).

  • Target
    HFE (Hemochromatosis (HFE))
    Alternative Name
    HFE (HFE Products)
    Synonyms
    HFE1 antibody, HH antibody, HLA-H antibody, MVCD7 antibody, TFQTL2 antibody, MR2 antibody, hemochromatosis antibody, HFE antibody, Hfe antibody
    Background

    Description: The protein encoded by this gene is a membrane protein that is similar to MHC class I-type proteins and associates with beta2-microglobulin (beta2M). It is thought that this protein functions to regulate iron absorption by regulating the interaction of the transferrin receptor with transferrin. The iron storage disorder, hereditary haemochromatosis, is a recessive genetic disorder that results from defects in this gene. At least nine alternatively spliced variants have been described for this gene. Additional variants have been found but their full-length nature has not been determined. 

    Aliases: HH, HFE1, HLA-H, MVCD7, TFQTL2, MGC103790, dJ221C16.10.1

    Molecular Weight
    40 kDa
    Gene ID
    3077
    HGNC
    3077
    Pathways
    Transition Metal Ion Homeostasis, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process
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