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HSP70 antibody (Heat Shock Protein 70)

Details for Product anti-HSP70 Antibody No. ABIN969201, Supplier: Log in to see
Antigen
  • HSP70
  • HEAT SHOCK PROTEIN 70
  • HEAT SHOCK PROTEIN 70-7
  • HSC70-7
  • K9P8.5
  • K9P8_5
  • chloroplast heat shock protein 70-2
  • cpHsc70-2
  • F19K16.12
  • F19K16_12
  • LOC100305036
  • hsc70
  • CG31354
  • Hsp70Bb
  • hsp70B
  • hsp70Bb-prime
  • DmelCG5834
  • CG5834
  • APG-2
  • HS24/P52
  • HSPH2
  • RY
  • hsp70
  • hsp70RY
  • hsc71
  • Hsp70
  • Hsp70-1
  • Hsp70.1
  • hsp68
  • Hsp110
  • irp94
  • HSPA1
  • HSP70B'
  • HSPA6
  • ARABIDOPSIS HEAT SHOCK PROTEIN 70
  • ATHSP70
  • heat shock protein 70
  • hsp70-5
Reactivity
Human
549
256
254
110
108
97
94
70
62
59
58
56
53
48
47
40
38
35
35
25
24
22
20
18
18
18
8
6
5
4
4
4
4
3
3
3
3
3
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
Host
Mouse
354
291
40
18
Clonality (Clone)
Monoclonal ()
Conjugate
This HSP70 antibody is un-conjugated
32
32
24
21
21
19
19
19
19
19
19
19
19
19
19
19
17
7
6
5
5
5
5
5
5
5
2
1
1
1
Application
Immunocytochemistry (ICC), Immunohistochemistry (IHC), ELISA, Western Blotting (WB)
617
274
249
249
234
218
89
75
55
51
25
18
12
9
3
2
2
1
Supplier
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Immunogen Purified recombinant fragment of human HSP70 expressed in E. coli.
Clone 5A6
Isotype IgG1
Purification Ascites
Alternative Name HSP70 (HSP70 Antibody Abstract)
Background This intronless gene encodes a 70 kDa heat shock protein which is a member of the heat shock protein 70 family. In conjuction with other heat shock proteins, this protein stabilizes existing proteins against aggregation and mediates the folding of newly translated proteins in the cytosol and in organelles. It is also involved in the ubiquitin-proteasome pathway through interaction with the AU-rich element RNA-binding protein 1. The gene is located in the major histocompatibility complex class III region, in a cluster with two closely related genes which encode similar proteins.
Molecular Weight 70 kDa
Gene ID 3308
HGNC 3308
Research Area Heat Shock Proteins
Pathways
Application Notes Recommended Dilution:
ELISA: 1/10000, WB: 1/500 - 1/2000, IHC: 1/200 - 1/1000, ICC: 1/200 - 1/1000
Not yet tested in other applications.
Determining optimal working dilutions by titration test.
Restrictions For Research Use only
Format Liquid
Buffer Ascitic fluid containing 0.03 % sodium azide.
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment Store at 4 °C or at -20 °C for long term.
Supplier Images
Immunocytochemistry (ICC) image for anti-HSP70 antibody (Heat Shock Protein 70) (ABIN969201) Figure 1: Immunofluorescence analysis of NIH/3T3 cells using HSP70 mouse mAb (green) ...
Immunohistochemistry (IHC) image for anti-HSP70 antibody (Heat Shock Protein 70) (ABIN969201) Figure 2: Immunohistochemical analysis of paraffin-embedded human breast cancer using...
Western Blotting (WB) image for anti-HSP70 antibody (Heat Shock Protein 70) (ABIN969201) Figure 3: Western blot analysis using HSP70 mouse mAb against Hela (1) cell lysate.
Product cited in: Elstrand, Kleinberg, Kohn et al.: "Expression and clinical role of antiapoptotic proteins of the bag, heat shock, and Bcl-2 families in effusions, primary tumors, and solid metastases in ovarian carcinoma." in: International journal of gynecological pathology : official journal of the International Society of Gynecological Pathologists, Vol. 28, Issue 3, pp. 211-21, 2009 (PubMed).

Di Tommaso, Destro, Seok et al.: "The application of markers (HSP70 GPC3 and GS) in liver biopsies is useful for detection of hepatocellular carcinoma." in: Journal of hepatology, Vol. 50, Issue 4, pp. 746-54, 2009 (PubMed).