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Details for Product No. ABIN969231

Kinase insert Domain Receptor (A Type III Receptor tyrosine Kinase) (KDR) (AA 20-764) antibody

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Antigen
Synonyms FLK1, CD309, VEGFR, VEGFR2, Vegfr-2, FLK-1, flk-1, FLK/KDR, vegfr-2, KDR
Epitope
»Alternatives AA 20-764
Reactivity
»Alternatives Human
Host
»Alternatives Mouse
Clonality (Clone) Monoclonal ()
Conjugate
»Alternatives Un-conjugated
Application
»Alternatives ELISA, Western Blotting (WB), Immunocytochemistry (ICC), Fluorescence Microscopy (FM)
Pubmed 1 reference available
Catalog no. ABIN969231
Quantity 100 µL
Price
363.00 $   Plus shipping costs $45.00
Shipping to
Availability Will be delivered in 3 to 4 Business Days
Immunogen Purified recombinant extracellular fragment of human KDR (AA 20-764) fused with hIgGFc tag expressed in HEK293 cells.
Clone 4B4
Isotype IgG1
Purification Ascites
Alternative Name KDR
Background Synonyms:
FLK1, CD309, VEGFR, VEGFR2
kDaR has also been designated as VEFR-2 (Vascular endothelial growth factor receptor 2), CD309 (cluster of differentiation 309) and Flk1 (fηl liver kinase 1). Vascular endothelial growth factor (VEGF) is a major growth factor for endothelial cells. kDaR is one of the two receptors of the VEGF. This receptor, known as kinase insert domain receptor, is a type III receptor tyrosine kinase. It functions as the main mediator of VEGF-induced endothelial proliferation, survival, migration, tubular morphogenesis and sprouting. The signalling and trafficking of this receptor are regulated by multiple factors, including Rab GTPase, P2Y purine nucleotide receptor, integrin αVβ3, T-cell protein tyrosine phosphatase, etc. . Mutations of this gene are implicated in infantile capillary hemangiomas.
Molecular Weight 152 kDa
Gene ID 3791
Application Notes Recommended Dilution:
ELISA: 1/10000, WB: 1/500 - 1/2000, ICC: 1/200 - 1/1000, FCM: 1/200 - 1/400
Not yet tested in other applications.
Determining optimal working dilutions by titration test.
Restrictions For Research Use only
Format Liquid
Buffer Ascitic fluid containing 0.03 % sodium azide.
Preservative Sodium azide
Storage 4 °C/-20 °C
Storage Comment Store at 4 °C or at -20 °C for long term.
Product cited in: Lee, Bone, Strege et al.: "VEGF receptor phosphorylation status and apoptosis is modulated by a green tea component, epigallocatechin-3-gallate (EGCG), in B-cell chronic lymphocytic leukemia." in: Blood, Vol. 104, Issue 3, pp. 788-94, 2004 (PubMed).

Alternatives for antigen "Kinase insert Domain Receptor (A Type III Receptor tyrosine Kinase) (KDR)", type "Antibodies"
Hosts (378), (77), (36), (3), (3), (2)
Reactivities (417), (261), (158), (18), (17), (14), (5), (3), (3), (3), (3), (3), (2), (2), (2), (2), (2), (1)
Applications (354), (156), (136), (122), (81), (77), (39), (38), (24), (20), (8), (7), (4), (4), (2), (2)
Conjugates (35), (6), (6), (6), (4), (4), (4), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1)
Epitopes (46), (39), (39), (26), (19), (16), (12), (11), (10), (7), (7), (6), (6), (5), (4), (4), (4), (4), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
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