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KLHL12 antibody

KLHL12 Reactivity: Human WB, ELISA Host: Mouse Monoclonal 2G2 unconjugated
Catalog No. ABIN969244
  • Target See all KLHL12 Antibodies
    KLHL12 (Kelch-Like 12 (Drosophila) (KLHL12))
    Reactivity
    • 37
    • 28
    • 5
    • 4
    • 4
    • 4
    • 4
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    Human
    Host
    • 48
    • 3
    • 1
    Mouse
    Clonality
    • 50
    • 2
    Monoclonal
    Conjugate
    • 18
    • 5
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    This KLHL12 antibody is un-conjugated
    Application
    • 39
    • 20
    • 13
    • 13
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    Western Blotting (WB), ELISA
    Purification
    purified
    Immunogen
    Purified recombinant fragment of human KLHL12 expressed in E. coli.
    Clone
    2G2
    Isotype
    IgG1
    Top Product
    Discover our top product KLHL12 Primary Antibody
  • Application Notes
    ELISA: 1:10000, WB: 1:500 - 1:2000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Ascitic fluid containing 0.03 % sodium azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C/-20 °C
    Storage Comment
    4°C, -20°C for long term storage
  • Jin, Pahuja, Wickliffe, Gorur, Baumgärtel, Schekman, Rape: "Ubiquitin-dependent regulation of COPII coat size and function." in: Nature, Vol. 482, Issue 7386, pp. 495-500, (2012) (PubMed).

  • Target
    KLHL12 (Kelch-Like 12 (Drosophila) (KLHL12))
    Alternative Name
    KLHL12 (KLHL12 Products)
    Synonyms
    zgc:92570 antibody, wu:fi60g03 antibody, C3ip1 antibody, C3IP1 antibody, DKIR antibody, hDKIR antibody, Ski2 like RNA helicase antibody, kelch like family member 12 L homeolog antibody, kelch like family member 12 antibody, kelch-like family member 12 antibody, kelch-like 12 antibody, SKIV2L antibody, klhl12.L antibody, KLHL12 antibody, klhl12 antibody, Klhl12 antibody
    Background

    Description: Serves as a substrate-specific adapter for the CUL3-based ubiquitin-protein E3 ligase complex. Negatively regulates the Wnt signaling pathway via the targeted ubiquitination and subsequent proteolysis of DVL3.Tissue specificity: Highly expressed in testis and at lower levels in the submandibular salivary gland.

    Aliases: DKIR, C3IP1, FLJ27152, KLHL12

    Molecular Weight
    63 kDa
    Gene ID
    59349
    HGNC
    59349
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