KLHL21 antibody

Catalog No. ABIN969246

Product Details anti-KLHL21 Antibody

Target: KLHL21 (Kelch-Like 21 (KLHL21))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This KLHL21 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Purification: purified

Immunogen: Purified recombinant fragment of human KLHL21 expressed in E. coli.

Clone: 2H4

Isotype: IgG1

Application Details

Application Notes: ELISA: 1:10000, WB: 1:500 - 1:2000, IHC: 1:200 - 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Ascitic fluid containing 0.03 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C/-20 °C

Storage Comment: 4°C, -20°C for long term storage

References for anti-KLHL21 antibody (ABIN969246)

Maerki, Olma, Staubli, Steigemann, Gerlich, Quadroni, Sumara, Peter: "The Cul3-KLHL21 E3 ubiquitin ligase targets aurora B to midzone microtubules in anaphase and is required for cytokinesis." in: The Journal of cell biology, Vol. 187, Issue 6, pp. 791-800, (2009) (PubMed).

Otsuki, Ota, Nishikawa, Hayashi, Suzuki, Yamamoto, Wakamatsu, Kimura, Sakamoto, Hatano, Kawai, Ishii, Saito, Kojima, Sugiyama, Ono, Okano, Yoshikawa, Aotsuka, Sasaki, Hattori, Okumura, Nagai, Sugano et al.: "Signal sequence and keyword trap in silico for selection of full-length human cDNAs encoding secretion or membrane proteins from oligo-capped cDNA libraries. ..." in: DNA research : an international journal for rapid publication of reports on genes and genomes, Vol. 12, Issue 2, pp. 117-26, (2005) (PubMed).

Target Details for KLHL21

Target: KLHL21 (Kelch-Like 21 (KLHL21))

Alternative Name: KLHL21 (KLHL21 Products)

Synonyms: zgc:76933 antibody, 1810045K06Rik antibody, D330008A20 antibody, mKIAA0469 antibody, RGD1305863 antibody, kelch-like family member 21 antibody, kelch like family member 21 antibody, kelch like family member 21 L homeolog antibody, kelch-like 21 antibody, klhl21 antibody, KLHL21 antibody, klhl21.L antibody, Klhl21 antibody

Background:

Description: Probable substrate-specific adapter of an E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins.

Aliases: KIAA0469, MGC99635, KLHL21

Molecular Weight: 66 kDa

Gene ID: 9903

HGNC: 9903

Pathways: M Phase