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Lysine (K)-Specific Demethylase 1A (KDM1A) antibody

Details for Product No. ABIN969264, Supplier: Log in to see
Antigen
  • KDM1
  • AOF2
  • KDM1A
  • DKFZp459N2450
  • aof2
  • kdm1
  • lsd1
  • xLSD1
  • BHC110
  • LSD1
  • 1810043O07Rik
  • AA408884
  • Aof2
  • D4Ertd478e
  • Kdm1
  • Lsd1
  • mKIAA0601
  • RGD1562975
  • wu:fb82e06
  • wu:fc51a02
  • wu:fj36a05
  • wu:fj66b06
  • ARABIDOPSIS LYSINE-SPECIFIC HISTONE DEMETHYLASE
  • ATLSD1
  • ATSWP1
  • F23N19.21
  • F23N19_21
  • LSD1-like 1
  • LYSINE-SPECIFIC HISTONE DEMETHYLASE
  • SWP1
Reactivity
Human, Mouse (Murine), Monkey
177
80
70
12
9
2
2
2
2
2
1
1
1
1
1
1
Host
Mouse
144
37
1
Clonality (Clone)
Monoclonal ()
Conjugate
Un-conjugated
2
2
2
2
2
2
2
2
2
2
2
2
Application
Immunohistochemistry (IHC), ELISA, Western Blotting (WB)
152
50
50
39
28
22
12
6
6
6
3
2
1
1
1
Supplier
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Immunogen Purified recombinant fragment of human LSD1 expressed in E. coli.
Clone 1B2E5
Isotype IgG1
Purification Ascites
Alternative Name LSD1/AOF2 (KDM1A Antibody Abstract)
Background The amine oxidase domain 2 (AOF2) gene encodes a nuclear protein (LSD1, ~95 kDa) containing a Swirm domain, a FAD-binding motif, and an amine oxidase domain. This protein is a component of several histone deacetylase complexes, though it silences genes by functioning as a histone demethylase. LSD1 is a chromatin-modifying enzyme, which serve as a docking module for the stabilization of the associated corepressor complex (es) on chromatin.
Molecular Weight 93 kDa
Gene ID 23028
HGNC 23028
Application Notes Recommended Dilution:
ELISA: 1/10000, WB: 1/500 - 1/2000, IHC: 1/200 - 1/1000
Not yet tested in other applications.
Determining optimal working dilutions by titration test.
Restrictions For Research Use only
Format Liquid
Buffer Ascitic fluid containing 0.03 % sodium azide.
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment Store at 4 °C or at -20 °C for long term.
Supplier Images
Immunohistochemistry (IHC) image for anti-Lysine (K)-Specific Demethylase 1A (KDM1A) antibody (ABIN969264) Figure 1: Immunohistochemical analysis of paraffin-embedded human lung carcinoma (lef...
Western Blotting (WB) image for anti-Lysine (K)-Specific Demethylase 1A (KDM1A) antibody (ABIN969264) Figure 2: Western blot analysis using LSD1 mouse mAb against COS (1), Hela (2), NIH/3...
Product cited in: Shi, Matson, Lan et al.: "Regulation of LSD1 histone demethylase activity by its associated factors." in: Molecular cell, Vol. 19, Issue 6, pp. 857-64, 2005 (PubMed).

Metzger, Wissmann, Yin et al.: "LSD1 demethylates repressive histone marks to promote androgen-receptor-dependent transcription." in: Nature, Vol. 437, Issue 7057, pp. 436-9, 2005 (PubMed).