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Lysine (K)-Specific Demethylase 1A (KDM1A) antibody

Details for Product No. ABIN969264, Supplier: Log in to see
Antigen
  • KDM1
  • AOF2
  • KDM1A
  • DKFZp459N2450
  • aof2
  • kdm1
  • lsd1
  • xLSD1
  • BHC110
  • LSD1
  • 1810043O07Rik
  • AA408884
  • Aof2
  • D4Ertd478e
  • Kdm1
  • Lsd1
  • mKIAA0601
  • RGD1562975
  • wu:fb82e06
  • wu:fc51a02
  • wu:fj36a05
  • wu:fj66b06
  • ARABIDOPSIS LYSINE-SPECIFIC HISTONE DEMETHYLASE
  • ATLSD1
  • ATSWP1
  • F23N19.21
  • F23N19_21
  • LSD1-like 1
  • LYSINE-SPECIFIC HISTONE DEMETHYLASE
  • SWP1
  • amine oxidase (flavin containing) domain 2
  • lysine (K)-specific demethylase 1
  • lysine (K)-specific demethylase 1A
  • lysine (K)-specific demethylase 1a
  • Lysine-specific histone demethylase 1-1
  • AOF2
  • KDM1
  • KDM1A
  • kdm1a
  • Kdm1a
  • LDL1
Alternatives
anti-Human Lysine (K)-Specific Demethylase 1A antibody for Chromatin Immunoprecipitation
Reactivity
Human, Mouse (Murine), Monkey
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125
99
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22
11
10
7
5
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3
2
2
2
1
1
1
1
Host
Mouse
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47
3
Clonality (Clone)
Monoclonal ()
Conjugate
Un-conjugated
2
2
2
2
2
2
2
2
2
2
2
2
2
2
Application
Immunohistochemistry (IHC), ELISA, Western Blotting (WB)
179
63
59
48
33
26
16
11
9
6
6
5
3
3
1
1
1
1
Options
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Immunogen Purified recombinant fragment of human LSD1 expressed in E. coli.
Clone 1B2E5
Isotype IgG1
Purification Ascites
Alternative Name LSD1/AOF2 (KDM1A Antibody Abstract)
Background The amine oxidase domain 2 (AOF2) gene encodes a nuclear protein (LSD1, ~95 kDa) containing a Swirm domain, a FAD-binding motif, and an amine oxidase domain. This protein is a component of several histone deacetylase complexes, though it silences genes by functioning as a histone demethylase. LSD1 is a chromatin-modifying enzyme, which serve as a docking module for the stabilization of the associated corepressor complex (es) on chromatin.
Molecular Weight 93 kDa
Gene ID 23028
HGNC 23028
Pathways Regulation of Hormone Metabolic Process, Regulation of Hormone Biosynthetic Process
Application Notes Recommended Dilution:
ELISA: 1/10000, WB: 1/500 - 1/2000, IHC: 1/200 - 1/1000
Not yet tested in other applications.
Determining optimal working dilutions by titration test.
Restrictions For Research Use only
Format Liquid
Buffer Ascitic fluid containing 0.03 % sodium azide.
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment Store at 4 °C or at -20 °C for long term.
Supplier Images
Immunohistochemistry (IHC) image for anti-Lysine (K)-Specific Demethylase 1A (KDM1A) antibody (ABIN969264) Figure 1: Immunohistochemical analysis of paraffin-embedded human lung carcinoma (lef...
Western Blotting (WB) image for anti-Lysine (K)-Specific Demethylase 1A (KDM1A) antibody (ABIN969264) Figure 2: Western blot analysis using LSD1 mouse mAb against COS (1), Hela (2), NIH/3...
Product cited in: Shi, Matson, Lan, Iwase, Baba, Shi: "Regulation of LSD1 histone demethylase activity by its associated factors." in: Molecular cell, Vol. 19, Issue 6, pp. 857-64, 2005 (PubMed).

Metzger, Wissmann, Yin, Müller, Schneider, Peters, Günther, Buettner, Schüle: "LSD1 demethylates repressive histone marks to promote androgen-receptor-dependent transcription." in: Nature, Vol. 437, Issue 7057, pp. 436-9, 2005 (PubMed).