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MAP3K2 antibody

MAP3K2 Reactivity: Human WB, ELISA, ICC Host: Mouse Monoclonal 4B4 unconjugated
Catalog No. ABIN969272
  • Target See all MAP3K2 Antibodies
    MAP3K2 (Mitogen-Activated Protein Kinase Kinase Kinase 2 (MAP3K2))
    Reactivity
    • 49
    • 29
    • 14
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    Human
    Host
    • 48
    • 2
    Mouse
    Clonality
    • 38
    • 12
    Monoclonal
    Conjugate
    • 23
    • 5
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    This MAP3K2 antibody is un-conjugated
    Application
    • 32
    • 20
    • 16
    • 6
    • 4
    • 3
    • 2
    • 2
    • 1
    Western Blotting (WB), ELISA, Immunocytochemistry (ICC)
    Purification
    purified
    Immunogen
    Purified recombinant fragment of human MAP3K2 expressed in E. coli.
    Clone
    4B4
    Isotype
    IgG1
  • Application Notes
    ELISA: 1:10000, WB: 1:500 - 1:2000, ICC: 1:200 - 1:1000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Ascitic fluid containing 0.03 % sodium azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C/-20 °C
    Storage Comment
    4°C, -20°C for long term storage
  • Kurada, Li, Mulherkar, Subramanian, Prasad, Prabhakar: "MADD, a splice variant of IG20, is indispensable for MAPK activation and protection against apoptosis upon tumor necrosis factor-alpha treatment." in: The Journal of biological chemistry, Vol. 284, Issue 20, pp. 13533-41, (2009) (PubMed).

    Cazares, Troyer, Mendrinos, Lance, Nyalwidhe, Beydoun, Clements, Drake, Semmes: "Imaging mass spectrometry of a specific fragment of mitogen-activated protein kinase/extracellular signal-regulated kinase kinase kinase 2 discriminates cancer from uninvolved prostate tissue." in: Clinical cancer research : an official journal of the American Association for Cancer Research, Vol. 15, Issue 17, pp. 5541-51, (2009) (PubMed).

  • Target
    MAP3K2 (Mitogen-Activated Protein Kinase Kinase Kinase 2 (MAP3K2))
    Alternative Name
    MAP3K2 (MAP3K2 Products)
    Synonyms
    Mekk2 antibody, MEKK2 antibody, MEKK2B antibody, 9630061B06Rik antibody, AI585793 antibody, Mekk2b antibody, mitogen activated protein kinase kinase kinase 2 antibody, mitogen-activated protein kinase kinase kinase 2 antibody, Map3k2 antibody, MAP3K2 antibody
    Background

    Description: The protein encoded by this gene is a member of serine/threonine protein kinase family. This kinase preferentially activates other kinases involved in the MAP kinase signaling pathway. This kinase has been shown to directly phosphorylate and activate Ikappa B kinases, and thus plays a role in NF-kappa B signaling pathway. This kinase has also been found to bind and activate protein kinase C-related kinase 2, which suggests its involvement in a regulated signaling process.

    Aliases: MEKK2, MEKK2B

    Molecular Weight
    70 kDa
    Gene ID
    10746
    HGNC
    10746
    Pathways
    MAPK Signaling
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