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MDM4-binding Protein antibody

MDM4 Reactivity: Human WB, ELISA, IHC, ICC Host: Mouse Monoclonal 2D10F4 unconjugated
Catalog No. ABIN969282
  • Target See all MDM4-binding Protein (MDM4) Antibodies
    MDM4-binding Protein (MDM4) (Mdm4-binding Protein (MDM4))
    Reactivity
    • 61
    • 41
    • 20
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    Human
    Host
    • 67
    • 8
    • 2
    Mouse
    Clonality
    • 72
    • 6
    Monoclonal
    Conjugate
    • 36
    • 6
    • 5
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    This MDM4-binding Protein antibody is un-conjugated
    Application
    • 57
    • 32
    • 13
    • 13
    • 11
    • 11
    • 9
    • 7
    • 3
    • 2
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunocytochemistry (ICC)
    Purification
    purified
    Immunogen
    Purified recombinant fragment of human MDM4 expressed in E. coli.
    Clone
    2D10F4
    Isotype
    IgG1
    Top Product
    Discover our top product MDM4 Primary Antibody
  • Application Notes
    ELISA: 1:10000, WB: 1:500 - 1:2000, IHC: 1:200 - 1:1000, ICC: 1:200 - 1:1000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Ascitic fluid containing 0.03 % sodium azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C/-20 °C
    Storage Comment
    4°C, -20°C for long term storage
  • Pan, Chen: "Modification of MDMX by sumoylation." in: Biochemical and biophysical research communications, Vol. 332, Issue 3, pp. 702-9, (2005) (PubMed).

    Wunderlich, Ghosh, Weghorst, Berberich: "MdmX represses E2F1 transactivation." in: Cell cycle (Georgetown, Tex.), Vol. 3, Issue 4, pp. 472-8, (2004) (PubMed).

  • Target
    MDM4-binding Protein (MDM4) (Mdm4-binding Protein (MDM4))
    Alternative Name
    MDM4 (MDM4 Products)
    Synonyms
    mdmx antibody, HDMX antibody, MDMX antibody, MRP1 antibody, wu:fa09h09 antibody, wu:fi33d10 antibody, 4933417N07Rik antibody, AA414968 antibody, AL023055 antibody, AU018793 antibody, AU021806 antibody, C85810 antibody, Mdmx antibody, MDM4, p53 regulator S homeolog antibody, MDM4, p53 regulator antibody, transformed mouse 3T3 cell double minute 4 antibody, mdm4.S antibody, MDM4 antibody, Mdm4 antibody, mdm4 antibody
    Background

    Description: MDM4, encodes a 490-amino acid protein containing a RING finger domain and a putative nuclear localization signal. The MDM4 putative nuclear localization signal, which all Mdm proteins contain, is located in the C-terminal region of the protein. The mRNA is expressed at a high level in thymus and at lower levels in all other tissues tested. MDM4 protein produced by in vitro translation interacts with p53 via a binding domain located in the N-terminal region of the MDM4 protein. MDM4 shows significant structural similarity to p53-binding protein MDM2.

    Aliases: HDMX, MDMX, MRP1, MDM4

    Molecular Weight
    55 kDa
    Gene ID
    4194
    HGNC
    4194
    Pathways
    Cell Division Cycle
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