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Details for Product No. ABIN969351

Peroxisome Proliferator-Activated Receptor Gamma, Coactivator 1 alpha (PPARGC1A) antibody

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Antigen
Synonyms AVPGC-1ALPHA, LEM6, PGC1, PGC1A, PGC-1v, PPARGC1, PGC-1(alpha), A830037N07Rik, ENSMUSG00000079510, Gm11133, PGC-1, Pgc-1alpha, Pgc1, Pgco1, Ppargc1, PPARGC1A
Reactivity
»Alternatives Human
Host
»Alternatives Mouse
Clonality (Clone) Monoclonal ()
Conjugate
»Alternatives Un-conjugated
Application
»Alternatives ELISA, Western Blotting (WB)
Pubmed 1 reference available
Catalog no. ABIN969351
Quantity 100 µL
Price
396.00 $   Plus shipping costs $45.00
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Availability Will be delivered in 3 to 4 Business Days
Immunogen Purified recombinant fragment of human PGC-1alpha expressed in E. coli.
Clone 1G8
Isotype IgG2b
Purification Ascites
Alternative Name PGC-1 alpha
Background Synonyms:
PPARGC1A, LEM6, PGC1, PGC1A, PGC-1v, PPARGC1, PGC-1 (α)
The protein encoded by this gene is a transcriptional coactivator that regulates the genes involved in energy mηbolism. This protein interacts with PPARγ, which permits the interaction of this protein with multiple transcription factors. This protein can interact with, and regulate the activities of, cAMP response element binding protein (CREB) and nuclear respiratory factors (NRFs). It provides a direct link between external physiological stimuli and the regulation of mitochondrial biogenesis, and is a major factor that regulates muscle fiber type determination. This protein may be also involved in controlling blood pressure, regulating cellular cholesterol homoeostasis, and the development of obesity.
Molecular Weight 91 kDa
Gene ID 10891
Application Notes Recommended Dilution:
ELISA: 1/10000, WB: 1/500 - 1/2000
Not yet tested in other applications.
Determining optimal working dilutions by titration test.
Restrictions For Research Use only
Format Liquid
Buffer Ascitic fluid containing 0.03 % sodium azide.
Preservative Sodium azide
Storage 4 °C/-20 °C
Storage Comment Store at 4 °C or at -20 °C for long term.
Product cited in: Barrès, Osler, Yan et al.: "Non-CpG methylation of the PGC-1alpha promoter through DNMT3B controls mitochondrial density." in: Cell metabolism, Vol. 10, Issue 3, pp. 189-98, 2009 (PubMed).

Alternatives for antigen "Peroxisome Proliferator-Activated Receptor Gamma, Coactivator 1 alpha (PPARGC1A)", type "Antibodies"
Hosts (46), (26), (7)
Reactivities (70), (30), (26), (23), (14), (14), (13), (2), (2), (1)
Applications (61), (35), (12), (10), (3), (2), (1), (1), (1), (1)
Conjugates (3), (3), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Epitopes (10), (6), (6), (4), (3), (3), (1), (1), (1), (1), (1)
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