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PPP1CA antibody

PPP1CA Reactivity: Human, Mouse WB, ELISA Host: Mouse Monoclonal 6D1 unconjugated
Catalog No. ABIN969359
  • Target See all PPP1CA Antibodies
    PPP1CA (Protein Phosphatase 1, Catalytic Subunit, alpha Isoform (PPP1CA))
    Reactivity
    • 74
    • 41
    • 41
    • 16
    • 10
    • 7
    • 5
    • 5
    • 3
    • 1
    • 1
    • 1
    • 1
    Human, Mouse
    Host
    • 50
    • 23
    • 2
    • 1
    Mouse
    Clonality
    • 53
    • 23
    Monoclonal
    Conjugate
    • 54
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    This PPP1CA antibody is un-conjugated
    Application
    • 49
    • 26
    • 16
    • 12
    • 11
    • 10
    • 10
    • 3
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA
    Purification
    purified
    Immunogen
    Purified recombinant fragment of human PPP1A expressed in E. coli.
    Clone
    6D1
    Isotype
    IgG1
  • Application Notes
    ELISA: 1:10000, WB: 1:500 - 1:2000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Ascitic fluid containing 0.03 % sodium azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C/-20 °C
    Storage Comment
    4°C, -20°C for long term storage
  • Luo, Peterson, Garcia, Coombs, Kofahl, Heinrich, Shabanowitz, Hunt, Yost, Virshup: "Protein phosphatase 1 regulates assembly and function of the beta-catenin degradation complex." in: The EMBO journal, Vol. 26, Issue 6, pp. 1511-21, (2007) (PubMed).

    Eto, Kirkbride, Elliott, Lo, Brautigan: "Association of the tensin N-terminal protein-tyrosine phosphatase domain with the alpha isoform of protein phosphatase-1 in focal adhesions." in: The Journal of biological chemistry, Vol. 282, Issue 24, pp. 17806-15, (2007) (PubMed).

  • Target
    PPP1CA (Protein Phosphatase 1, Catalytic Subunit, alpha Isoform (PPP1CA))
    Alternative Name
    PPP1A (PPP1CA Products)
    Synonyms
    PP-1A antibody, PP1A antibody, PP1alpha antibody, PPP1A antibody, Ppp1c antibody, dism2 antibody, ppp1a antibody, wu:fc04c08 antibody, wu:fc09b07 antibody, wu:fc30g11 antibody, wu:fe05h08 antibody, zgc:85729 antibody, Ppp1ca antibody, fb18b03 antibody, fd20h04 antibody, wu:fb18b03 antibody, wu:fd20h04 antibody, wu:fl22a03 antibody, zgc:55744 antibody, zgc:76940 antibody, protein phosphatase 1 catalytic subunit alpha antibody, protein phosphatase 1, catalytic subunit, alpha isoform antibody, protein phosphatase 1, catalytic subunit, alpha isozyme L homeolog antibody, protein phosphatase 1, catalytic subunit, alpha isozyme antibody, protein phosphatase 1, catalytic subunit, alpha isozyme a antibody, protein phosphatase 1, catalytic subunit, alpha isozyme b antibody, PPP1CA antibody, Ppp1ca antibody, ppp1ca.L antibody, ppp1ca antibody, ppp1caa antibody, ppp1cab antibody
    Background

    Description: The protein encoded by this gene is one of the three catalytic subunits of protein phosphatase 1 (PP1). PP1 is a serine/threonine specific protein phosphatase known to be involved in the regulation of a variety of cellular processes, such as cell division, glycogen metabolism, muscle contractility, protein synthesis, and HIV-1 viral transcription. Increased PP1 activity has been observed in the end stage of heart failure. Studies in both human and mice suggest that PP1 is an important regulator of cardiac function. Mouse studies also suggest that PP1 functions as a suppressor of learning and memory. Three alternatively spliced transcript variants encoding different isoforms have been found for this gene.

    Aliases: PP-1A, PPP1A, MGC1674, MGC15877, PP1alpha, PPP1CA

    Molecular Weight
    38 kDa
    Gene ID
    5499
    HGNC
    5499
    Pathways
    M Phase, Cellular Glucan Metabolic Process, Regulation of Carbohydrate Metabolic Process, Lipid Metabolism
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