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Endogenous Retrovirus Group K, Member 10 (ERVK-10) antibody

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Synonyms PR, Protease, Proteinase
(1), (1)
(1), (1)
Clonality (Clone)
Monoclonal ()
Immunohistochemistry (IHC), ELISA, Western Blotting (WB)
(2), (2), (1), (1)
Pubmed 6 references available
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Quantity 100 μL
Shipping to United States ( )
Availability Will be delivered in 3 to 4 Business Days
Immunogen Purified recombinant fragment of PR expressed in E. coli.
Clone 2F12B4
Isotype IgG1
Purification Ascites
Alternative Name PR
Background PR(progesterone receptor), with 933-amino acid protein (about 110 kDa), a member of the steroid receptor superfamily, mediates the physiologic effects of progesterone, PR is mediated by two functionally different isoforms of the progesterone receptor, the full length PR-B and the short form PR-A. The PR-A and PR-B proteins are 94 kDa and 114 kDa respectively. That are equimolar in the normal breast but dysregulated in advanced disease. PR is prognostic markers in breast cancers irrespective of the patient's progestational status Human progesterone.
Gene ID 5241
HGNC 5241
Application Notes Recommended Dilution:
ELISA: 1/10000, WB: 1/500 - 1/2000, IHC: 1/200 - 1/1000
Not yet tested in other applications.
Determining optimal working dilutions by titration test.
Restrictions For Research Use only
Format Liquid
Buffer Ascitic fluid containing 0.03 % sodium azide.
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment Store at 4 °C or at -20 °C for long term.
Supplier Images
Immunohistochemistry (IHC) image for anti-Endogenous Retrovirus Group K, Member 10 (ERVK-10) antibody (ABIN969361) Figure 1: Immunohistochemical analysis of paraffin-embedded human infiltrating ductal...
Western Blotting (WB) image for anti-Endogenous Retrovirus Group K, Member 10 (ERVK-10) antibody (ABIN969361) Figure 2: Western blot analysis using PR mouse mAb against PR recombinant protein (1) .
Product cited in: Jowett: "Safe Motherhood interventions in low-income countries: an economic justification and evidence of cost effectiveness." in: Health policy (Amsterdam, Netherlands), Vol. 53, Issue 3, pp. 201-28, 2000 (PubMed).

McLachlan, Jelinek, Kummerfeld et al.: "Cross-sectional infarct edge jaggedness does not influence ventricular electrical stability in a rabbit model of late myocardial infarct healing." in: Redox report : communications in free radical research, Vol. 5, Issue 2-3, pp. 122-3, 2000 (PubMed).

Bach: "Markets in kidneys." in: Lancet, Vol. 2, Issue 8411, pp. 1102, 1984 (PubMed).

Background publications Wen, Xu, Mais et al.: "The A and B isoforms of the human progesterone receptor operate through distinct signaling pathways within target cells." in: Molecular and cellular biology, Vol. 14, Issue 12, pp. 8356-64, 1994 (PubMed).

Clark, Osborne, McGuire: "Correlations between estrogen receptor, progesterone receptor, and patient characteristics in human breast cancer." in: Journal of clinical oncology : official journal of the American Society of Clinical Oncology, Vol. 2, Issue 10, pp. 1102-9, 1984 (PubMed).

McGuire: "Prognostic factors in primary breast cancer." in: Cancer surveys, Vol. 5, Issue 3, pp. 527-36, 1987 (PubMed).

Catalog No. ABIN969361
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