PR antibody

Details for Product No. ABIN969361, Supplier: Log in to see
Clonality (Clone)
Monoclonal ()
Immunohistochemistry (IHC), ELISA, Western Blotting (WB)
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Immunogen Purified recombinant fragment of PR expressed in E. Coli.
Clone 2F12B4
Isotype IgG1
Purification Ascites
Background PR(progesterone receptor), with 933-amino acid protein (about 110 kDa), a member of the steroid receptor superfamily, mediates the physiologic effects of progesterone, PR is mediated by two functionally different isoforms of the progesterone receptor, the full length PR-B and the short form PR-A. The PR-A and PR-B proteins are 94 kDa and 114 kDa respectively. That are equimolar in the normal breast but dysregulated in advanced disease. PR is prognostic markers in breast cancers irrespective of the patient's progestational status Human progesterone.
Gene ID 5241
HGNC 5241
Application Notes ELISA: 1:10000, WB: 1:500 - 1:2000, IHC: 1:200 - 1:1000
Restrictions For Research Use only
Format Liquid
Buffer Ascitic fluid containing 0.03 % sodium azide.
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C,-20 °C
Storage Comment 4°C, -20°C for long term storage
Supplier Images
Immunohistochemistry (IHC) image for anti-PR antibody (ABIN969361) Figure 1: Immunohistochemical analysis of paraffin-embedded human infiltrating ductal...
Western Blotting (WB) image for anti-PR antibody (ABIN969361) Figure 2: Western blot analysis using PR mouse mAb against PR recombinant protein (1) .
Product cited in: Jowett: "Safe Motherhood interventions in low-income countries: an economic justification and evidence of cost effectiveness." in: Health policy (Amsterdam, Netherlands), Vol. 53, Issue 3, pp. 201-28, 2000 (PubMed).

McLachlan, Jelinek, Kummerfeld, Rummery, Jusuf, Hambly, McGuire: "Cross-sectional infarct edge jaggedness does not influence ventricular electrical stability in a rabbit model of late myocardial infarct healing." in: Redox report : communications in free radical research, Vol. 5, Issue 2-3, pp. 122-3, 2000 (PubMed).

Bach: "Markets in kidneys." in: Lancet, Vol. 2, Issue 8411, pp. 1102, 1984 (PubMed).

Background publications Wen, Xu, Mais, Goldman, McDonnell: "The A and B isoforms of the human progesterone receptor operate through distinct signaling pathways within target cells." in: Molecular and cellular biology, Vol. 14, Issue 12, pp. 8356-64, 1994 (PubMed).

McGuire: "Prognostic factors in primary breast cancer." in: Cancer surveys, Vol. 5, Issue 3, pp. 527-36, 1987 (PubMed).

Clark, Osborne, McGuire: "Correlations between estrogen receptor, progesterone receptor, and patient characteristics in human breast cancer." in: Journal of clinical oncology : official journal of the American Society of Clinical Oncology, Vol. 2, Issue 10, pp. 1102-9, 1984 (PubMed).