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Progesterone Receptor antibody (PGR)

Details for Product anti-PGR Antibody No. ABIN969361, Supplier: Log in to see
Antigen
  • PR
  • XPR-1
  • pgr
  • xpr-2
  • PGR
  • pg
  • pr
  • gb:dq017620
  • NR3C3
  • 9930019P03Rik
  • BB114106
  • ENSMUSG00000074510
  • PR-A
  • PR-B
  • LOC443444
Alternatives
anti-Human Progesterone Receptor antibody for Immunohistochemistry (Paraffin-embedded Sections)
Reactivity
Human
574
70
68
15
6
5
4
3
2
2
1
Host
Mouse
335
251
3
Clonality (Clone)
Monoclonal ()
Conjugate
This Progesterone Receptor antibody is un-conjugated
16
15
13
8
8
8
3
2
2
2
2
2
2
2
2
1
Application
Immunohistochemistry (IHC), ELISA, Western Blotting (WB)
408
155
152
145
104
49
45
26
24
9
7
3
3
3
2
2
1
1
1
1
1
Supplier
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Immunogen Purified recombinant fragment of PR expressed in E. coli.
Clone 2F12B4
Isotype IgG1
Purification Ascites
Alternative Name PR (PGR Antibody Abstract)
Background PR(progesterone receptor), with 933-amino acid protein (about 110 kDa), a member of the steroid receptor superfamily, mediates the physiologic effects of progesterone, PR is mediated by two functionally different isoforms of the progesterone receptor, the full length PR-B and the short form PR-A. The PR-A and PR-B proteins are 94 kDa and 114 kDa respectively. That are equimolar in the normal breast but dysregulated in advanced disease. PR is prognostic markers in breast cancers irrespective of the patient's progestational status Human progesterone.
Gene ID 5241
HGNC 5241
Pathways Nuclear Receptor Transcription Pathway
Application Notes Recommended Dilution:
ELISA: 1/10000, WB: 1/500 - 1/2000, IHC: 1/200 - 1/1000
Not yet tested in other applications.
Determining optimal working dilutions by titration test.
Restrictions For Research Use only
Format Liquid
Buffer Ascitic fluid containing 0.03 % sodium azide.
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment Store at 4 °C or at -20 °C for long term.
Supplier Images
Immunohistochemistry (IHC) image for anti-Progesterone Receptor antibody (PGR) (ABIN969361) Figure 1: Immunohistochemical analysis of paraffin-embedded human infiltrating ductal...
Western Blotting (WB) image for anti-Progesterone Receptor antibody (PGR) (ABIN969361) Figure 2: Western blot analysis using PR mouse mAb against PR recombinant protein (1) .
Product cited in: Jowett: "Safe Motherhood interventions in low-income countries: an economic justification and evidence of cost effectiveness." in: Health policy (Amsterdam, Netherlands), Vol. 53, Issue 3, pp. 201-28, 2000 (PubMed).

McLachlan, Jelinek, Kummerfeld et al.: "Cross-sectional infarct edge jaggedness does not influence ventricular electrical stability in a rabbit model of late myocardial infarct healing." in: Redox report : communications in free radical research, Vol. 5, Issue 2-3, pp. 122-3, 2000 (PubMed).

Bach: "Markets in kidneys." in: Lancet, Vol. 2, Issue 8411, pp. 1102, 1984 (PubMed).

Background publications Wen, Xu, Mais et al.: "The A and B isoforms of the human progesterone receptor operate through distinct signaling pathways within target cells." in: Molecular and cellular biology, Vol. 14, Issue 12, pp. 8356-64, 1994 (PubMed).

Clark, Osborne, McGuire: "Correlations between estrogen receptor, progesterone receptor, and patient characteristics in human breast cancer." in: Journal of clinical oncology : official journal of the American Society of Clinical Oncology, Vol. 2, Issue 10, pp. 1102-9, 1984 (PubMed).

McGuire: "Prognostic factors in primary breast cancer." in: Cancer surveys, Vol. 5, Issue 3, pp. 527-36, 1987 (PubMed).