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SET Domain, Bifurcated 1 (SETDB1) antibody

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Synonyms SETDB1, NV10069, fc07d03, si:ch211-81a5.6, wu:fc07d03, ESET, H3-K9-HMTase4, KG1T, KMT1E, TDRD21, AU022152, mKIAA0067
Human, Mouse (Murine), Monkey
(93), (33), (20), (9)
(70), (23)
Clonality (Clone)
Monoclonal ()
(3), (3), (3), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1)
ELISA, Western Blotting (WB)
(78), (44), (20), (11), (9), (9), (7), (5), (3), (3), (1)
Pubmed 2 references available
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Quantity 100 μL
Shipping to United States ( )
Availability Will be delivered in 3 to 4 Business Days
Immunogen Purified recombinant fragment of human SETDB1 expressed in E. coli.
Clone 5H6D4
Isotype IgG1
Purification Ascites
Alternative Name SETDB1 (SETDB1 Antibody Abstract)
Background This gene encodes a histone methyltransferase. The encoded enzyme catalyzes the reaction of S-adenosyl-L-methionine and histone L-lysine to produce S-adenosyl-L-homocysteine and histone N(6)-methyl-L-lysine. The encoded protein likely functions in transcriptional repression.Tissue specificity: Widely expressed. High expression in testis.
Molecular Weight 180 kDa
Gene ID 9869
HGNC 9869
Application Notes Recommended Dilution:
ELISA: 1/10000, WB: 1/500 - 1/2000
Not yet tested in other applications.
Determining optimal working dilutions by titration test.
Restrictions For Research Use only
Format Liquid
Buffer Ascitic fluid containing 0.03 % sodium azide.
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment Store at 4 °C or at -20 °C for long term.
Supplier Images
Western Blotting (WB) image for anti-SET Domain, Bifurcated 1 (SETDB1) antibody (ABIN969393) Figure 1: Western blot analysis using SETDB1 mouse mAb against MCF-7 (1) ,T47D (2), H...
Product cited in: Gevaert, Staes, Van Damme et al.: "Global phosphoproteome analysis on human HepG2 hepatocytes using reversed-phase diagonal LC." in: Proteomics, Vol. 5, Issue 14, pp. 3589-99, 2005 (PubMed).

Background publications Rosendorff, Sakakibara, Lu et al.: "NXP-2 association with SUMO-2 depends on lysines required for transcriptional repression." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 103, Issue 14, pp. 5308-13, 2006 (PubMed).

Catalog No. ABIN969393
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