SOX2 antibody (SRY (Sex Determining Region Y)-Box 2) (AA 1-170)

Details for Product anti-SOX2 Antibody No. ABIN969413, Supplier: Log in to see
Antigen
  • Qscn6
  • Qsox
  • Sox-2
  • rSOx
  • ANOP3
  • MCOPS3
  • RGD1565646
  • SRY-box2
  • Xsox-2
  • anop3
  • mcops3
  • sox-2
  • lcc
  • ysb
  • cb236
  • wu:fb83g04
  • wu:fc14d07
  • zgc:65860
  • zgc:77389
  • SRY (sex determining region Y)-box 2
  • quiescin Q6 sulfhydryl oxidase 1
  • SRY-box containing gene 2
  • LOC100231711
  • Qsox1
  • SOX2
  • Sox2
  • sox2
Alternatives
anti-Human SOX2 antibody for Biochemical Assay
Epitope
AA 1-170
58
21
19
18
16
15
14
14
13
11
6
5
5
5
5
4
4
4
4
3
3
3
3
3
3
2
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
Reactivity
Human
448
164
84
32
28
20
15
13
13
12
10
9
9
6
5
4
4
3
2
2
1
1
1
1
1
Host
Mouse
292
163
7
Clonality (Clone)
Monoclonal ()
Conjugate
This SOX2 antibody is un-conjugated
21
19
19
16
11
11
9
9
8
8
6
6
4
4
4
4
4
3
3
3
3
3
2
1
1
Application
ELISA, Western Blotting (WB)
316
172
130
129
129
96
88
56
17
7
7
6
4
4
2
2
2
1
1
1
1
1
1
Options
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Immunogen Purified recombinant fragment of SOX2 (aa1-170) expressed in E. Coli.
Clone 10F10C9
Isotype IgG1
Purification Ascites
Alternative Name SOX2 (SOX2 Antibody Abstract)
Background SOX2: SRY (sex determining region Y)-box 2. Entrez Protein NP_003097. It is a member of the SRY-related HMG-box (SOX) family of transcription factors involved in the regulation of embryonic development and in the determination of cell fate. The product of this gene is required for stem-cell maintenance in the central nervous system, and also regulates gene expression in the stomach. Mutations in this gene have been associated with optic nerve hypoplasia and with syndromic microphthalmia, a severe form of structural eye malformation. This gene lies within an intron of another gene called SOX2 overlapping transcript (SOX2OT).
Molecular Weight 34.3 kDa
Gene ID 6657
HGNC 6657
Research Area Embryogenesis, Embryonic stem cells, Reproduction, Transcription Factors, Neural Stem Cell marker
Pathways Dopaminergic Neurogenesis, Sensory Perception of Sound, Stem Cell Maintenance, Cell RedoxHomeostasis
Application Notes ELISA: 1:10000, WB: 1:500 - 1:2000
Restrictions For Research Use only
Format Liquid
Buffer Ascitic fluid containing 0.03 % sodium azide.
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C,-20 °C
Storage Comment 4°C, -20°C for long term storage
Supplier Images
Western Blotting (WB) image for anti-SOX2 antibody (SRY (Sex Determining Region Y)-Box 2) (AA 1-170) (ABIN969413) Figure 1: Western blot analysis using SOX2 mouse mAb against truncated Trx-SOX2 recom...
Product cited in: Park, Zhao, West, Yabuuchi, Huo, Ince, Lerou, Lensch, Daley: "Reprogramming of human somatic cells to pluripotency with defined factors." in: Nature, Vol. 451, Issue 7175, pp. 141-6, 2008 (PubMed).

Baer, Eriksson, Faull, Rees, Curtis: "Sox-2 is expressed by glial and progenitor cells and Pax-6 is expressed by neuroblasts in the human subventricular zone." in: Experimental neurology, Vol. 204, Issue 2, pp. 828-31, 2007 (PubMed).