SRY (Sex Determining Region Y)-Box 2 (SOX2) (AA 1-170) antibody

Details for Product No. ABIN969413
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Antigen
Synonyms Qscn6, Qsox, Sox-2, rSOx, ANOP3, MCOPS3, RGD1565646, SRY-box2, Xsox-2, anop3, mcops3, sox-2, lcc, ysb, cb236, wu:fb83g04, wu:fc14d07, zgc:65860, zgc:77389
Epitope
AA 1-170
(42), (9), (9), (8), (7), (6), (6), (4), (4), (4), (4), (4), (3), (3), (3), (3), (3), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity
Human
(202), (64), (43), (20), (20), (20), (16), (12), (5), (4), (4), (3), (3), (2), (1), (1), (1)
Host
Mouse
(166), (44), (4)
Clonality (Clone)
Monoclonal ()
Conjugate
Un-conjugated
(11), (6), (6), (6), (5), (5), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application
ELISA, Western Blotting (WB)
(150), (70), (42), (33), (31), (30), (26), (26), (11), (10), (10), (9), (5), (3), (1)
Pubmed 2 references available
Quantity 100 μL
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Catalog No. ABIN969413
319.00 $
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Immunogen Purified recombinant fragment of SOX2 (AA 1-170) expressed in E. coli.
Clone 10F10C9
Isotype IgG1
Purification Ascites
Alternative Name SOX2
Background Synonyms:
ANOP3, MCOPS3, MGC2413
SOX2: SRY (sex determining region Y) -box 2. It is a member of the SRY-related HMG-box (SOX) family of transcription factors involved in the regulation of embryonic development and in the determination of cell fate. The product of this gene is required for stem-cell maintenance in the central nervous system, and also regulates gene expression in the stomach. Mutations in this gene have been associated with optic nerve hypoplasia and with syndromic microphthalmia, a severe form of structural eye malformation. This gene lies within an intron of another gene called SOX2 overlapping transcript (SOX2OT).
Molecular Weight 34.3 kDa
Gene ID 6657
Research Area Embryogenesis, Embryonic stem cells, Reproduction, Transcription Factors, Neural Stem Cell marker
Application Notes Recommended Dilution:
ELISA: 1/10000, WB: 1/500 - 1/2000
Not yet tested in other applications.
Determining optimal working dilutions by titration test.
Restrictions For Research Use only
Format Liquid
Buffer Ascitic fluid containing 0.03 % sodium azide.
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment Store at 4 °C or at -20 °C for long term.
Supplier Images
anti-SRY (Sex Determining Region Y)-Box 2 (SOX2) (AA 1-170) antibody Figure 1: Western blot analysis using SOX2 mouse mAb against truncated Trx-SOX2 recombinant protein (1) and truncated MBP-SOX2 (aa1-170) recombinant protein (2) .
Product cited in: Baer, Eriksson, Faull et al.: "Sox-2 is expressed by glial and progenitor cells and Pax-6 is expressed by neuroblasts in the human subventricular zone." in: Experimental neurology, Vol. 204, Issue 2, pp. 828-31, 2007 (PubMed).

Park, Zhao, West et al.: "Reprogramming of human somatic cells to pluripotency with defined factors." in: Nature, Vol. 451, Issue 7175, pp. 141-6, 2008 (PubMed).

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