SOX2 antibody (SRY (Sex Determining Region Y)-Box 2)

Details for Product anti-SOX2 Antibody No. ABIN969414, Supplier: Log in to see
Antigen
  • Qscn6
  • Qsox
  • Sox-2
  • rSOx
  • ANOP3
  • MCOPS3
  • RGD1565646
  • SRY-box2
  • Xsox-2
  • anop3
  • mcops3
  • sox-2
  • lcc
  • ysb
  • cb236
  • wu:fb83g04
  • wu:fc14d07
  • zgc:65860
  • zgc:77389
  • SRY (sex determining region Y)-box 2
  • quiescin Q6 sulfhydryl oxidase 1
  • SRY-box containing gene 2
  • LOC100231711
  • Qsox1
  • SOX2
  • Sox2
  • sox2
Alternatives
anti-Human SOX2 antibody for Western Blotting
Reactivity
Human
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2
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Host
Mouse
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7
Clonality (Clone)
Monoclonal ()
Conjugate
This SOX2 antibody is un-conjugated
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Application
Immunocytochemistry (ICC), Immunohistochemistry (IHC), ELISA, Western Blotting (WB)
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96
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17
7
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Options
Supplier
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Supplier Product No.
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Immunogen Purified recombinant fragment of human SOX2 expressed in E. Coli.
Clone 10F10
Isotype IgG1
Purification Ascites
Alternative Name SOX2 (SOX2 Antibody Abstract)
Background Transcription factor that forms a trimeric complex with OCT4 on DNA and controls the expression of a number of genes involved in embryonic development such as YES1, FGF4, UTF1 and ZFP206. Critical for early embryogenesis and for embryonic stem cell pluripotency.
Molecular Weight 34 kDa
Gene ID 20674
HGNC 20674
Research Area Embryogenesis, Embryonic stem cells, Reproduction, Transcription Factors, Neural Stem Cell marker
Pathways Dopaminergic Neurogenesis, Sensory Perception of Sound, Stem Cell Maintenance, Cell RedoxHomeostasis
Application Notes ELISA: 1:10000, WB: 1:500 - 1:2000, IHC: 1:200 - 1:1000, ICC: 1:200 - 1:1000
Restrictions For Research Use only
Format Liquid
Buffer Ascitic fluid containing 0.03 % sodium azide.
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C,-20 °C
Storage Comment 4°C, -20°C for long term storage
Supplier Images
Immunocytochemistry (ICC) image for anti-SRY (Sex Determining Region Y)-Box 2 (SOX2) antibody (ABIN969414) Figure 1:
Immunocytochemistry (ICC) image for anti-SRY (Sex Determining Region Y)-Box 2 (SOX2) antibody (ABIN969414) Figure 2: Immunofluorescence analysis of NTERA-2 cells using SOX2 mouse mAb (green) ....
Immunohistochemistry (IHC) image for anti-SRY (Sex Determining Region Y)-Box 2 (SOX2) antibody (ABIN969414) Figure 3: Immunohistochemical analysis of paraffin-embedded lung cancer tissues (left...
Western Blotting (WB) image for anti-SRY (Sex Determining Region Y)-Box 2 (SOX2) antibody (ABIN969414) Figure 4: Western blot analysis using SOX2 mAb against HEK293 (1) and SOX2 (AA: 2-317...
Product cited in: Dabdoub, Puligilla, Jones, Fritzsch, Cheah, Pevny, Kelley: "Sox2 signaling in prosensory domain specification and subsequent hair cell differentiation in the developing cochlea." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 105, Issue 47, pp. 18396-401, 2008 (PubMed).

Qin, Gan, Shao, Wang, Li, Wang, He, Xu, Zhang, Kou, Zeng, Sheng, Esteban, Gao, Pei: "Mouse meningiocytes express Sox2 and yield high efficiency of chimeras after nuclear reprogramming with exogenous factors." in: The Journal of biological chemistry, Vol. 283, Issue 48, pp. 33730-5, 2008 (PubMed).

Tay, Zhang, Thomson, Lim, Rigoutsos: "MicroRNAs to Nanog, Oct4 and Sox2 coding regions modulate embryonic stem cell differentiation." in: Nature, Vol. 455, Issue 7216, pp. 1124-8, 2008 (PubMed).

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