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Details for Product No. ABIN969555

Phosphoinositide-3-Kinase, Catalytic, alpha Polypeptide (PIK3CA) antibody

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Antigen
Synonyms CLOVE, CWS5, MCAP, MCM, MCMTC, PI3K, p110-alpha, 6330412C24Rik, caPI3K, p110, p110alpha, C-P3K, PI3-kinase, PI3K-alpha, pi3-k, pi3k
Reactivity
»Alternatives Human
Host
»Alternatives Mouse
Clonality (Clone) Monoclonal ()
Conjugate
»Alternatives Un-conjugated
Application
»Alternatives ELISA, Western Blotting (WB), Immunocytochemistry (ICC), Fluorescence Microscopy (FM)
Pubmed 2 references available
Catalog no. ABIN969555
Quantity 0.1 mg
Price
396.00 $   Plus shipping costs $45.00
Shipping to
Availability Will be delivered in 3 to 4 Business Days
Immunogen Purified recombinant fragment of human PIK3CA expressed in E. coli.
Clone 4F3
Isotype IgG1
Purification Purified
Alternative Name PIK3CA
Background Synonyms:
PI3K, p110-α
Phosphatidylinositol 3-kinase is composed of an 85 kDa regulatory subunit and a 110 kDa catalytic subunit. The protein encoded by this gene represents the catalytic subunit, which uses ATP to phosphorylate PtdIns, PtdIns4P and PtdIns (4,5)P2. This gene has been found to be oncogenic and has been implicated in cervical cancers.
Molecular Weight 124 kDa
Gene ID 5290
Application Notes Recommended Dilution:
ELISA: 1/10000, WB: 1/500 - 1/2000, ICC: 1/200 - 1/1000, FCM: 1/200 - 1/400
Not yet tested in other applications.
Determining optimal working dilutions by titration test.
Restrictions For Research Use only
Format Liquid
Buffer PBS with 0.05 % sodium azide and 0.5 % protein stabilizer
Preservative Sodium azide
Storage 4 °C/-20 °C
Storage Comment Store at 4 °C or at -20 °C for long term.
Product cited in: Edwards, Witherspoon, Wang et al.: "Epigenetic repression of DNA mismatch repair by inflammation and hypoxia in inflammatory bowel disease-associated colorectal cancer." in: Cancer research, Vol. 69, Issue 16, pp. 6423-9, 2009 (PubMed).

Pang, Flinn, Patsialou et al.: "Differential enhancement of breast cancer cell motility and metastasis by helical and kinase domain mutations of class IA phosphoinositide 3-kinase." in: Cancer research, Vol. 69, Issue 23, pp. 8868-76, 2009 (PubMed).

Alternatives for antigen "Phosphoinositide-3-Kinase, Catalytic, alpha Polypeptide (PIK3CA)", type "Antibodies"
Hosts (47), (8), (6)
Reactivities (60), (29), (23), (14), (12), (2), (1)
Applications (35), (32), (24), (10), (9), (6), (4), (4), (3), (2), (1)
Conjugates (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Epitopes (13), (3), (2), (1), (1), (1), (1)
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