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Thrombopoietin antibody (THPO)

Details for Product anti-THPO Antibody No. ABIN969571, Supplier: Log in to see
Antigen
  • tpo
  • LOC100231762
  • TPO
  • MGDF
  • MKCSF
  • ML
  • MPLLG
  • THCYT1
  • Mgdf
  • Ml
  • Mpllg
  • Tpo
  • Tpo1
  • Tpo2
  • Tpo3
  • Tpo4
Alternatives
anti-Human Thrombopoietin antibody for Enzyme Immunoassay
Reactivity
Human
104
42
8
2
1
1
1
1
Host
Mouse
75
31
25
16
Clonality (Clone)
Monoclonal ()
Conjugate
This Thrombopoietin antibody is un-conjugated
11
7
3
2
2
2
1
Application
Flow Cytometry (FACS), ELISA, Western Blotting (WB)
105
93
12
10
10
9
7
6
5
5
3
2
2
2
Supplier
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Immunogen Purified recombinant fragment of human THPO expressed in E. coli.
Clone 1B11
Isotype IgG2a
Purification Purified
Alternative Name THPO (THPO Antibody Abstract)
Background Megakaryocytopoiesis is the cellular development process that leads to platelet production. The protein encoded by this gene is a humoral growth factor that is necessary for megakaryocyte proliferation and maturation, as well as for thrombopoiesis. This protein is the ligand for MLP/C_MPL, the product of myeloproliferative leukemia virus oncogene. Alternate splicing results in multiple transcript variants of this gene.
Molecular Weight 37.8 kDa
Gene ID 7066
HGNC 7066
Pathways JAK-STAT Signaling
Application Notes Recommended Dilution:
ELISA: 1/10000, WB: 1/500 - 1/2000, FCM: 1/200 - 1/400
Not yet tested in other applications.
Determining optimal working dilutions by titration test.
Restrictions For Research Use only
Format Liquid
Buffer PBS with 0.05 % sodium azide and 0.5 % protein stabilizer
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment Store at 4 °C or at -20 °C for long term.
Supplier Images
ELISA image for anti-Thrombopoietin antibody (THPO) (ABIN969571) Figure 1: Red: Control Antigen (100 ng), Purple: Antigen (10ng), Green: Antigen (50 n...
Flow Cytometry (FACS) image for anti-Thrombopoietin antibody (THPO) (ABIN969571) Figure 2: Flow cytometric analysis of MCF-7 cells using THPO mouse mAb (green) and ne...
Western Blotting (WB) image for anti-Thrombopoietin antibody (THPO) (ABIN969571) Figure 3: Western blot analysis using THPO mAb against human THPO (AA: 250-303) recom...
Product cited in: Graziano, Carone, Panza et al.: "Association of hereditary thrombocythemia and distal limb defects with a thrombopoietin gene mutation." in: Blood, Vol. 114, Issue 8, pp. 1655-7, 2009 (PubMed).

Eissa, Gad, Rabie et al.: "Thrombopoietin level in patients with chronic liver diseases." in: Annals of hepatology, Vol. 7, Issue 3, pp. 235-44, 2008 (PubMed).