Thrombopoietin (THPO) antibody

Details for Product No. ABIN969571
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Antigen
Synonyms tpo, LOC100231762, TPO, MGDF, MKCSF, ML, MPLLG, THCYT1, Mgdf, Ml, Mpllg, Tpo, Tpo1, Tpo2, Tpo3, Tpo4
Reactivity
Human
(78), (43), (13), (12), (4), (1), (1), (1), (1)
Host
Mouse
(67), (24), (20), (7)
Clonality (Clone)
Monoclonal ()
Conjugate
Un-conjugated
(7), (5), (3), (1), (1), (1), (1), (1), (1), (1), (1)
Application
ELISA, Western Blotting (WB), Fluorescence Microscopy (FM)
(75), (67), (13), (12), (10), (7), (6), (5), (3), (3), (3), (2), (2), (2), (2), (1)
Pubmed 1 reference available
Quantity 0.1 mg
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Catalog No. ABIN969571
396.00 $
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Immunogen Purified recombinant fragment of human THPO expressed in E. coli.
Clone 1B11
Isotype IgG2a
Purification Purified
Alternative Name THPO
Background Synonyms:
ML, TPO, MGDF, MKCSF, MPLLG
Megakaryocytopoiesis is the cellular development process that leads to platelet production. The protein encoded by this gene is a humoral growth factor that is necessary for megakaryocyte proliferation and maturation, as well as for thrombopoiesis. This protein is the ligand for MLP/C_MPL, the product of myeloproliferative leukemia virus oncogene. Alternate splicing results in multiple transcript variants of this gene.
Molecular Weight 37.8 kDa
Gene ID 7066
Application Notes Recommended Dilution:
ELISA: 1/10000, WB: 1/500 - 1/2000, FCM: 1/200 - 1/400
Not yet tested in other applications.
Determining optimal working dilutions by titration test.
Restrictions For Research Use only
Format Liquid
Buffer PBS with 0.05 % sodium azide and 0.5 % protein stabilizer
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment Store at 4 °C or at -20 °C for long term.
Supplier Images
anti-Thrombopoietin (THPO) antibody Red: Control Antigen (100 ng), Purple: Antigen (10ng), Green: Antigen (50 ng), Blue: Antigen (100 ng)
anti-Thrombopoietin (THPO) antibody (2) Figure 2: Flow cytometric analysis of MCF-7 cells using THPO mouse mAb (green) and negative control (red) .
anti-Thrombopoietin (THPO) antibody (3) Figure 1: Western blot analysis using THPO mAb against human THPO (AA: 250-303) recombinant protein. (Expected MW is 30 kDa)
Product cited in: Graziano, Carone, Panza et al.: "Association of hereditary thrombocythemia and distal limb defects with a thrombopoietin gene mutation." in: Blood, Vol. 114, Issue 8, pp. 1655-7, 2009 (PubMed).

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