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Signal Transducer and Activator of Transcription 6, Interleukin-4 Induced (STAT6) antibody

Antigen

Signal Transducer and Activator of Transcription 6, Interleukin-4 Induced (STAT6)
Synonyms STAT6B, STAT6C, D12S1644, IL-4-STAT
Clonality Monoclonal
Host
Alternatives

Mouse
Reactivity
Alternatives

Human
Conjugate
Alternatives Un-conjugated
Application
Alternatives Western Blotting (WB)
1 reference available
Catalog no. ABIN970004
Quantity 100 µg  (Variants)
Price 273.90 $   Plus shipping costs $45.00
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anti-Signal Transducer and Activator of Transcription 6, Interleukin-4 Induced (STAT6) antibody

Additional Information
Application Details Publications Images Alternatives Variants back to top

Alternative name STAT6
Gene ID STAT6
Format Lyophilized
Reconstitution Add distilled water.
Isotype IgG
Description STAT6 is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein plays a central role in exerting IL4 mediated biological responses. It is found to induce the expression of BCL2L1/BCL-X(L), which is responsible for the anti-apoptotic activity of IL4. Knockout studies in mice suggested the roles of this gene in differentiation of T helper 2 (Th2) cells, expression of cell surface markers, and class switch of immunoglobulins.
Characteristics Antigen Size: 847 amino acids
Molecular Weight 94kDa

Application Details
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Application Notes WB Suggested Anti-STAT6 Antibody Titration: 1.0ug/ml
Positive Control: ACHN cell lysate
Buffer PBS
Storage (Long Term) For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
Storage (Short Term) Any unfrozen and/or unused material can be stored at 4°C for short term use (< 1 week), and should not be re-frozen.
Restrictions For Research Use only

Publications
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Product Takeda, Tanaka, Shi et al.: "Essential role of Stat6 in IL-4 signalling." in: Nature, Vol. 380, Issue 6575, pp. 627-30, 1996 (PubMed).

Alternatives
Application Details Publications Images Variants back to top

Alternatives for antigen "Signal Transducer and Activator of Transcription 6, Interleukin-4 Induced (STAT6)", type "Antibodies"
Hosts Rabbit (130), Mouse (27), Chicken (2)
Reactivities Human (151), Rat (Rattus) (50), Mouse (Murine) (47), Pig (Porcine) (7), Cow (Bovine) (5), Horse (Equine) (5), Dog (Canine) (3), Monkey (3)
Applications Western Blotting (WB) (114), ELISA (48), Immunohistochemistry (IHC) (45), Immunofluorescence (IF) (32), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (28), Immunoprecipitation (IP) (25), Flow Cytometry (FACS) (9), Immunocytochemistry (ICC) (6), Immunohistochemistry (Formalin-fixed Sections) (IHC (f)) (3), Fluorescence Microscopy (FM) (2), Immunoassay (IA) (1), Immunoelectron Microscopy (IEM) (1), Immunohistochemistry (Fixed) (IHC (fx)) (1)
Conjugates Alexa Fluor 350 (3), Alexa Fluor 488 (3), Alexa Fluor 555 (3), Alexa Fluor 647 (3), PE,Cy5.5 (3), PE (2), APC (1), Biotin (1), Cy3 (1), Cy5 (1), Cy5.5 (1), Cy7 (1), FITC (1), Gold (1), HRP (1), PE,Cy3 (1), PE,Cy5 (1), PE,Cy7 (1)
Epitopes pTyr641 (24), pThr645 (15), C-Term (11), AA 808-826 (4), Tyr641 (4), AA 630-650 (3), AA 342-640 (2), AA 806-826 (2), Internal Region (2), Thr645 (2), pTyr641,Internal Region (2), AA 61-275 (1), AA 620 (1), N-Term (1), Phosphospecific (1), pThr641 (1), pTyr642 (1), pTyr694 (1), phospho (1)