TRIM3 antibody (Middle Region)

Catalog No. ABIN971929

Product Details anti-TRIM3 Antibody

Target: TRIM3 (Tripartite Motif Containing 3 (TRIM3))

Binding Specificity: Middle Region

Reactivity: Human, Mouse, Rat, Cow, Dog, Rabbit, Guinea Pig, Horse, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TRIM3 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: VKRRVKSPGG PGSHVRQKAV RRPSSMYSTG GKRKDNPIED ELVFRVGSRG

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 93%, Rat: 100%, Zebrafish: 79%

Characteristics: This is a rabbit polyclonal antibody against TRIM3. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human TRIM3

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 744 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for TRIM3

Target: TRIM3 (Tripartite Motif Containing 3 (TRIM3))

Alternative Name: TRIM3 (TRIM3 Products)

Synonyms: BERP antibody, HAC1 antibody, RNF22 antibody, RNF97 antibody, BERP1 antibody, Rnf22 antibody, Berp antibody, zgc:153967 antibody, tripartite motif containing 3 antibody, tripartite motif-containing 3 antibody, tripartite motif containing 3 S homeolog antibody, tripartite motif containing 3b antibody, TRIM3 antibody, Trim3 antibody, trim3.S antibody, trim3b antibody

Background: The protein encoded by this gene is a member of the tripartite motif (TRIM) family, also called the 'RING-B-box-coiled-coil' (RBCC) subgroup of RING finger proteins. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. This protein localizes to cytoplasmic filaments. It is similar to a rat protein which is a specific partner for the tail domain of myosin V, a class of myosins which are involved in the targeted transport of organelles. The rat protein can also interact with alpha-actinin-4. Thus it is suggested that this human protein may play a role in myosin V-mediated cargo transport. Alternatively spliced transcript variants encoding the same isoform have been identified.
Alias Symbols: BERP, FLJ16135, HAC1, RNF22, RNF97
Protein Interaction Partner: CUL3, UBC, HECW2, KIF21B, TNFAIP3, HGS, MYO5A, ACTN4, UBE2D4, UBE2U, UBE2G2, TRIM3, UBE2K,
Protein Size: 744

Molecular Weight: 81 kDa

Gene ID: 10612

NCBI Accession: NM_006458, NP_006449

UniProt: O75382