tyrosine 3-Monooxygenase/tryptophan 5-Monooxygenase Activation Protein, eta Polypeptide (YWHAH) (N-Term) antibody

Details for Product No. ABIN972023
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Antigen
Synonyms YWHA1, 14-3-3e, ywha1, YWHAH
Epitope
N-Term
(7), (3), (2), (1), (1)
Reactivity
Rabbit, Mouse (Murine), Rat (Rattus), Cow (Bovine), Xenopus laevis, Human, Chicken
(31), (15), (14), (6), (4), (3), (3), (1)
Host
Rabbit
(28), (6)
Clonality
Polyclonal
Application
Immunohistochemistry (IHC), Western Blotting (WB)
(34), (14), (11), (7), (7), (5), (1), (1)
Pubmed 2 references available
Catalog no. ABIN972023
Quantity 50 µg
Price
289.00 $   Plus shipping costs $45.00
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Immunogen Synthetic peptide directed towards the N terminal of human YWHAH
Sequence ADGNEKKLEKVKAYREKIEKELETVCNDVLSLLDKFLIKN CNDFQYESKV
Predicted Reactivity Chicken : 100 %, Dog : 100 %, Human : 100 %, Rabbit : 100 %, African clawed frog : 90 %, Zebrafish : 70 %
Characteristics This is a rabbit polyclonal antibody against YWHAH. It was validated on Western Blot and immunohistochemistry.
Purification Affinity Purified
Alternative Name YWHAH
Background The YWHAH gene product belongs to the 14-3-3 family of proteins which mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals, and this protein is 99 % identical to the mouse, rat and bovine orthologs. This gene contains a 7 bp repeat sequence in its 5' UTR, and changes in the number of this repeat has been associated with early-onset schizophrenia.This gene product belongs to the 14-3-3 family of proteins which mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals, and this protein is 99 % identical to the mouse, rat and bovine orthologs. This gene contains a 7 bp repeat sequence in its 5' UTR, and changes in the number of this repeat has been associated with early-onset schizophrenia.
Molecular Weight 28 kDa
Gene ID 7533
NCBI Accession NM_003405, NP_003396
UniProt Q04917
Application Notes Optimal working dilutions should be determined experimentally by the investigator.
Comment

Antigen size: 246 AA

Restrictions For Research Use only
Format Lyophilized
Reconstitution Add 50 µL of distilled water.
Concentration 1 mg/mL
Buffer PBS buffer with 2 % sucrose
Handling Advice Avoid repeated freeze-thaw cycles.
Storage -20 °C
Storage Comment For longer periods of storage, store at -20 °C
Supplier Images
anti-tyrosine 3-Monooxygenase/tryptophan 5-Monooxygenase Activation Protein, eta Polypeptide (YWHAH) (N-Term) antibody anti-tyrosine 3-Monooxygenase/tryptophan 5-Monooxygenase Activation Protein, eta Polypeptide (YWHAH) (N-Term) antibody
Product cited in: Ubl, Berg, Holzmann et al.: "14-3-3 protein is a component of Lewy bodies in Parkinson's disease-mutation analysis and association studies of 14-3-3 eta." in: Brain research. Molecular brain research, Vol. 108, Issue 1-2, pp. 33-9, 2002 (PubMed).

Background publications Hoger, Rudy, Lester et al.: "Characterization of maintained voltage-dependent K(+)-channels induced in Xenopus oocytes by rat brain mRNA." in: Brain research. Molecular brain research, Vol. 10, Issue 1, pp. 1-11, 1991 (PubMed).

Hosts (28), (6)
Reactivities (31), (15), (14), (6), (4), (3), (3), (1)
Applications (34), (14), (11), (7), (7), (5), (1), (1)
Epitopes (7), (3), (2), (1), (1)
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