Cyclin A (CCNA) antibody

Antigen: Cyclin A (CCNA)

Synonyms: CCNA2, Cyca, CycA, 0033/02, 0040/24, 0046/23, 0104/07, 0245/34, 0521/06, 0545/13, 1329/16, 1449/05, DmcycA, S(rux)3B, anon-WO0140519.128, cycA, hari, l(3)03946, l(3)183, l(3)68Ea, l(3)j3C8, l(3)neo114, l(3)rsg11, rsg11, DmelCG5940, CG5940

Clonality: Monoclonal (6-00E-006)

Host: Mouse

Reactivity: Human

Application: Immunohistochemistry (IHC)

Catalog no.: ABIN97946

Additional Information

Alternative name: Cyclin A

Immunogen: Synthetic peptide corresponding to the N-terminal fragment of cyclin A protein.

Format: Supernatant

Isotype: IgG1 kappa  (Matching secondary antibodies)

Clone: 6-00E-006

Specificity: This antibody may be used to examine the biological behavior of tumors. Cyclins are proteins that vary in abundance and are associated with and activate cyclin dependent kinases at different stages of the cell cycle. Cyclin A is detectable in S phase increasing during progression into G2 phase. Increased expression of various cyclins have been noted in some human cancers.

Synonyms: CCNA2, Cyca, CycA, 0033/02, 0040/24, 0046/23, 0104/07, 0245/34, 0521/06, 0545/13, 1329/16, 1449/05, DmcycA, S(rux)3B, anon-WO0140519.128, cycA, hari, l(3)03946, l(3)183, l(3)68Ea, l(3)j3C8, l(3)neo114, l(3)rsg11, rsg11, DmelCG5940, CG5940

Application Details

Application Notes: Titer/Working Dilution: This antibody may be diluted to a titer of 1:20-1:40 in an ABC method. However, depending on the staining conditions employed, we suggest that final dilution should be determined by the user. Positive Control: Tonsil. Cellular localization: Nuclear Other Applications: Immunoprecipitation, Western blotting (1:100-500).

Concentration: 100ug/ml approximately

Buffer: This antibody is supplied as tissue culture supernatant containing sodium azide as preservative.

Storage: Store the antibody at 2-8o c. Do not use it beyond the expiration date stated on the label.

Research Area: Cell Cycle

Restrictions: For Research Use. CE-certified for In Vitro Diagnostics (IVD) Use in the European Union

Images

Formalin fixed paraffin embedded human tonsil stained with Cyclin A antibody

Publications

Publications: Bodey, Williams, Carbonaro-Hall et al.: "Immunocytochemical detection of cyclin A and cyclin D in formalin-fixed, paraffin-embedded tissues: novel, pertinent markers of cell proliferation." in: Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc, Vol. 7, Issue 8, pp. 846-52, 1995 (PubMed).

Inohara, Kitano: "Immunohistochemical detection of cyclin D and cyclin A in human hyperproliferative epidermis." in: Archives of dermatological research, Vol. 286, Issue 8, pp. 504-6, 1995 (PubMed).