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Produktdetails für  11beta-Hydroxysteroid Dehydrogenase (Type 2) antibody

11beta-Hydroxysteroid Dehydrogenase (Type 2) antibody

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Antigen: 11beta-Hydroxysteroid Dehydrogenase (Type 2)
Antikörper-Typ: Polyklonal
Applikation: Western Blotting (WB), Immunocytochemistry (ICC)
Reaktivität: Human, Mouse (Murine)
Wirt: Rabbit
Menge: 1 ea
Preis: 254,00 €   (Zzgl. Versandkosten und MWSt)
Bestellnummer: ABIN110240
Verfügbarkeit: 1 to 7 days before shipment
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Produktbeschreibung:  11beta-Hydroxysteroid Dehydrogenase (Type 2) antibody

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Antigen 11beta-Hydroxysteroid Dehydrogenase (Type 2)
Immunogen Human 11beta-Hydroxysteroid dehydrogenase (Type 2) (11beta-HSD2) amino acids
Reaktivität Human, Mouse (Murine)
Antikörper-Typ Polyklonal
Beschreibung 11beta-HSD2 plays a critical role in normal physiology in the corticosteroid regulation of sodium homeostasis and the pathophysiology of hypertension by converting active cortisol to inactive cortisone. Mutation in the gene encoding 11beta-HSD2 results in cortisol induction of hypertension and hypokalemia, a syndrome of apparent mineralocorticoid excess. 11beta-HSD2 mRNA and protein are expressed in placenta and mineralocorticoid target tissues, particularly the kidney. In mouse, expression of this enzyme is tissue-specific and developmentally regulated, indicating the importance of the enzyme in controlling glucocorticoid-mediated maturation. Cayman's 11beta-HSD2 polyclonal antibody can be used for western blotting and immunochemical analysis of 11beta-HSD2 from samples of human, rat, and mouse. The antibody detects a band at 44 kDa in tissues such as kidney and cell lines including Caco-2 cells and HT-29 cells.
Wirt Rabbit
Spezifität Human 11beta-HSD2: +, murine 11beta-HSD2: +, rat 11beta-HSD2: +

Anwendungen:  11beta-Hydroxysteroid Dehydrogenase (Type 2) antibody

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Applikation Western Blotting (WB), Immunocytochemistry (ICC)
Buffer Affinity-purified IgG
Lagerung 1 year
Forschungsgebiet Enzymes
Beschränkungen For Research only

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