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Product details for 11beta-Hydroxysteroid Dehydrogenase (Type 2) antibody
11beta-Hydroxysteroid Dehydrogenase (Type 2) antibody
Overview
| Antigen: | 11beta-Hydroxysteroid Dehydrogenase (Type 2) |
| Antibody Type: | Polyclonal |
| Application: | Western Blotting (WB), Immunocytochemistry (ICC) |
| Reactivity: | Human, Mouse (Murine) |
| Host: | Rabbit |
| Quantity: | |
| Price: | 254,00 € (Plus shipping costs and VAT) |
| Order number: | ABIN110240 |
| Availability: | 1 to 7 days before shipment |
Additional Information: 11beta-Hydroxysteroid Dehydrogenase (Type 2) antibody
| Antigen | 11beta-Hydroxysteroid Dehydrogenase (Type 2) |
| Immunogen | Human 11beta-Hydroxysteroid dehydrogenase (Type 2) (11beta-HSD2) amino acids |
| Reactivity | Human, Mouse (Murine) |
| Antibody Type | Polyclonal |
| Description | 11beta-HSD2 plays a critical role in normal physiology in the corticosteroid regulation of sodium homeostasis and the pathophysiology of hypertension by converting active cortisol to inactive cortisone. Mutation in the gene encoding 11beta-HSD2 results in cortisol induction of hypertension and hypokalemia, a syndrome of apparent mineralocorticoid excess. 11beta-HSD2 mRNA and protein are expressed in placenta and mineralocorticoid target tissues, particularly the kidney. In mouse, expression of this enzyme is tissue-specific and developmentally regulated, indicating the importance of the enzyme in controlling glucocorticoid-mediated maturation. Cayman's 11beta-HSD2 polyclonal antibody can be used for western blotting and immunochemical analysis of 11beta-HSD2 from samples of human, rat, and mouse. The antibody detects a band at 44 kDa in tissues such as kidney and cell lines including Caco-2 cells and HT-29 cells. |
| Host | Rabbit |
| Specificity | Human 11beta-HSD2: +, murine 11beta-HSD2: +, rat 11beta-HSD2: + |
Application Details: 11beta-Hydroxysteroid Dehydrogenase (Type 2) antibody
| Application | Western Blotting (WB), Immunocytochemistry (ICC) |
| Buffer | Affinity-purified IgG |
| Storage | 1 year |
| Research Area | Enzymes |
| Restrictions | For Research only |
External Information: 11beta-Hydroxysteroid Dehydrogenase (Type 2) antibody
| Google Scholar | Find more references for antigen 11beta-Hydroxysteroid Dehydrogenase (Type 2) on Google Scholar™ |
| EMBL Harvester | Search human, mouse or rat genome for antigen 11beta-Hydroxysteroid Dehydrogenase (Type 2) (Bioinformatic Harvester (EMBL)) |
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