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Produktdetails für  14-3-3 (Human) antibody

14-3-3 (Human) antibody

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Antigen: 14.03.2003
Antikörper-Typ: Polyklonal
Applikation: Immunohistochemistry ((Frozen Sections) (IHC) (fro)), Immunohistochemistry (Formalin-fixed Sections) (IHC (f)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunoprecipitation (IP), Western Blotting (WB)
Reaktivität: Human, Mouse (Murine), Rat
Wirt: Rabbit
Menge: 1 ml (0.2 mg/ml)
Preis: 330,00 €   (Zzgl. Versandkosten und MWSt)
Bestellnummer: ABIN150104
Verfügbarkeit: 7 to 10 days until shipment
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Produktbeschreibung:  14-3-3 (Human) antibody

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Antigen 14.03.2003
Immunogen Synthetic peptide mapping to the amino terminal domain of human 14-3-3.
Reaktivität Human, Mouse (Murine), Rat
Antikörper-Typ Polyklonal
Isotyp IgG »Passende Sekundärantikörper
Beschreibung Members of the 14-3-3 family of proteins are highly conserved proteins, localized in neurons, and are axonally transported to the nerve terminals. They are also present, at lower levels, in various other eukaryotic tissues. 14-3-3 proteins appear to play important roles in a variety of signal transduction pathways, including those involved in cell cycle regulation and cell survival. Because 14-3-3 proteins bind to specific phosphoserine-containing sequences they are likely to have an important role in signaling pathways mediated by serine/threonine protein kinases. Evidence indicates 14-3-3 is required for Raf-1 kinase activity and phosphorylation amoung many other functions.
Wirt Rabbit
Spezifität Broadly reactive among the 14-3-3 family.

Anwendungen:  14-3-3 (Human) antibody

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Applikation Immunohistochemistry ((Frozen Sections) (IHC) (fro)), Immunohistochemistry (Formalin-fixed Sections) (IHC (f)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunoprecipitation (IP), Western Blotting (WB)
Applikationshinweise IHC-P: Use at an assay dependent dilution. IP: Use at an assay dependent dilution. WB: Use at a dilution of 1/400. Predicted molecular weight: 27-30k band and will cross react with alpha, beta, zeta, and theta isoforms, but is most strongly reactive with the Beta form. Not tested in other applications. Optimal dilutions/concentrations should be determined by the end user.
Konzentration 0.2 mg/ml
Reinheit Immunogen affinity purified
Buffer Preservative: 0.1% Sodium AzideConstituents: 0.2% Gelatin, PBS
Lagerung Keep as concentrated solution, aliquot and store at 4C. Do not freeze.
Forschungsgebiet Transcription Factors
Beschränkungen For research use only

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