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Product details for 14-3-3 (Human) antibody
14-3-3 (Human) antibody
Overview
| Antigen: | 14.03.2003 |
| Antibody Type: | Polyclonal |
| Application: | Immunohistochemistry ((Frozen Sections) (IHC) (fro)), Immunohistochemistry (Formalin-fixed Sections) (IHC (f)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunoprecipitation (IP), Western Blotting (WB) |
| Reactivity: | Human, Mouse (Murine), Rat |
| Host: | Rabbit |
| Quantity: | |
| Price: | 330,00 € (Plus shipping costs and VAT) |
| Order number: | ABIN150104 |
| Availability: | 7 to 10 days until shipment |
Additional Information: 14-3-3 (Human) antibody
| Antigen | 14.03.2003 |
| Immunogen | Synthetic peptide mapping to the amino terminal domain of human 14-3-3. |
| Reactivity | Human, Mouse (Murine), Rat |
| Antibody Type | Polyclonal |
| Isotype | IgG »Matching secondary antibodies |
| Description | Members of the 14-3-3 family of proteins are highly conserved proteins, localized in neurons, and are axonally transported to the nerve terminals. They are also present, at lower levels, in various other eukaryotic tissues. 14-3-3 proteins appear to play important roles in a variety of signal transduction pathways, including those involved in cell cycle regulation and cell survival. Because 14-3-3 proteins bind to specific phosphoserine-containing sequences they are likely to have an important role in signaling pathways mediated by serine/threonine protein kinases. Evidence indicates 14-3-3 is required for Raf-1 kinase activity and phosphorylation amoung many other functions. |
| Host | Rabbit |
| Specificity | Broadly reactive among the 14-3-3 family. |
Application Details: 14-3-3 (Human) antibody
| Application | Immunohistochemistry ((Frozen Sections) (IHC) (fro)), Immunohistochemistry (Formalin-fixed Sections) (IHC (f)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunoprecipitation (IP), Western Blotting (WB) |
| Application Notes | IHC-P: Use at an assay dependent dilution. IP: Use at an assay dependent dilution. WB: Use at a dilution of 1/400. Predicted molecular weight: 27-30k band and will cross react with alpha, beta, zeta, and theta isoforms, but is most strongly reactive with the Beta form. Not tested in other applications. Optimal dilutions/concentrations should be determined by the end user. |
| Concentration | 0.2 mg/ml |
| Purity | Immunogen affinity purified |
| Buffer | Preservative: 0.1% Sodium AzideConstituents: 0.2% Gelatin, PBS |
| Storage | Keep as concentrated solution, aliquot and store at 4C. Do not freeze. |
| Research Area | Transcription Factors |
| Restrictions | For research use only |
External Information: 14-3-3 (Human) antibody
| Google Scholar | Find more references for antigen 14.03.2003 on Google Scholar™ |
| EMBL Harvester | Search human, mouse or rat genome for antigen 14.03.2003 (Bioinformatic Harvester (EMBL)) |
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