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Product details for 14-3-3 Protein pSer58 (Human) antibody
14-3-3 Protein pSer58 (Human) antibody
Overview
| Antigen: | 14-3-3 Protein pSer58 |
| Antibody Type: | Polyclonal |
| Application: | Western Blotting (WB) |
| Reactivity: | Human, Mouse (Murine), Rat, Xenopus |
| Host: | Rabbit |
| Quantity: | |
| Price: | 350,00 € (Plus shipping costs and VAT) |
| Order number: | ABIN152092 |
| Availability: | Ships in 7 to 10 days |
Additional Information: 14-3-3 Protein pSer58 (Human) antibody
| Antigen | 14-3-3 Protein pSer58 |
| Immunogen | Phosphopeptide corresponding to amino acid residues surrounding the phospho-Ser58of rat 14-3-3 protein. |
| Reactivity | Human, Mouse (Murine), Rat, Xenopus |
| Antibody Type | Polyclonal |
| Format | Aff - Purified |
| Description | 14-3-3 proteins are a family of highly conserved proteins that appear to have multipleroles in cell signaling. The proteins are abundantly expressed in the brain and havebeen detected in the cerebrospinal fluid of patients with different neurological disorders. 14-3-3 proteins bind protein ligands that are typically phosphorylated on serine orthreonine residues and regulate the functions of these binding partners by a number ofdifferent mechanisms. The 14-3-3 proteins affect a diverse array of cellular processesincluding the cell cycle and transcription, signal transduction and intracellular trafficking. These functions of 14-3-3 proteins are facilitated by, if not dependent on, its dimericstructure. Recent work has demonstrated that the dimeric status of the 14-3-3 protein isregulated by site-specific serine phosphorylation. (1-5) Synonyms: Protein kinase C inhibitor protein 1 antibody, KCIP-1 antibody |
| Host | Rabbit |
| Specificity | Human, mouse, Xenopus, and rat based on 100% antigen sequence homology. |
Application Details: 14-3-3 Protein pSer58 (Human) antibody
| Application | Western Blotting (WB) |
| Application Notes | WB - 1:1,000*The investigator should determine the optimal working dilution for a specific application. This antibody has been tested in Western blot on rat brain hippocampal lysate, detectinga band ~29 kDa. No other applications have been tested.Recommended Starting |
| Buffer | 0.1 ml of affinity purified rabbit sera. Concentration is unknown. Adequate amount ofmaterial to conduct 10-mini Western blots. 10 mM Hepes (pH7.5), 150 mM NaCl, 100 ug/ml BSA and 50% glycerol |
| Storage | Store at -20 degrees C. Stable for 1 year. |
| Restrictions | For Research Use only |
External Information: 14-3-3 Protein pSer58 (Human) antibody
| Google Scholar | Find more references for antigen 14-3-3 Protein pSer58 on Google Scholar™ |
| EMBL Harvester | Search human, mouse or rat genome for antigen 14-3-3 Protein pSer58 (Bioinformatic Harvester (EMBL)) |
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