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Product details for 14-3-3 beta + zeta (Human) antibody
14-3-3 beta + zeta (Human) antibody
Overview
| Antigen: | 14-3-3 beta + zeta |
| Antibody Type: | Monoclonal |
| Application: | Immunocytochemistry (ICC), Immunohistochemistry (IHC), Western Blotting (WB) |
| Reactivity: | Human, Mouse (Murine), Rat, Dog (Canine), Rabbit, Bovine |
| Host: | Mouse |
| Quantity: | |
| Price: | 271,00 € (Plus shipping costs and VAT) |
| Order number: | ABIN145161 |
| Availability: | 7 to 10 days until shipment |
Additional Information: 14-3-3 beta + zeta (Human) antibody
| Antigen | 14-3-3 beta + zeta |
| Immunogen | Lysed transformed amnion cells (AMA) (Human). |
| Reactivity | Human, Mouse (Murine), Rat, Dog (Canine), Rabbit, Bovine |
| Antibody Type | Monoclonal |
| Format | Lyophilized |
| Isotype | IgG »Matching secondary antibodies |
| Description | 14-3-3 proteins are highly conserved proteins which play a role in both signal transduction and progression through the cell cycle by binding to and regulating several different proteins. 14-3-3 proteins activate tyrosine and tryptophan hydroxylases and protein kinase C. They mediate signal transduction by binding to phosphoserine-containing proteins. There are at least 7 mammalian isoforms: alpha, beta, gamma, delta, epsilon, zeta, and eta. An eighth subtype, termed theta has been found in rat brain. The 14-3-3 proteins exist in vitro and in vivo as either homo- or heterodimers which interact via their N-terminal domains and are subject to phosphorylation by protein kinase C. 14-3-3 proteins are localized in the cytoplasm of neurons in the cerebral cortex and are axonally transported to the nerve terminals. They may be present at lower levels in various other eukaryotic tissues. Northern blot analysis has shown expression of the eta chain in cultured cell lines derived from vario |
| Clone | 22-IID8B |
| Host | Mouse |
Application Details: 14-3-3 beta + zeta (Human) antibody
| Application | Immunocytochemistry (ICC), Immunohistochemistry (IHC), Western Blotting (WB) |
| Application Notes | ICC: Use at an assay dependent dilution. IHC: Use at a dilution of 1/50. WB: Use at a concentration of 1 ug/ml. Predicted molecular weight: 29 and 30 kDa. Not tested in other applications. Optimal dilutions/concentrations should be determined by the end user. |
| Purity | Protein G purified |
| Buffer | Preservative: NoneConstituents: 50% Glycerol, PBS, 0.1mM PMSF. pH 7.2 |
| Storage | Store at 4 C. Aliquot and store at -20 C long-term. |
| Restrictions | For research use only |
External Information: 14-3-3 beta + zeta (Human) antibody
| Google Scholar | Find more references for clone 22-IID8B on Google Scholar™ |
| EMBL Harvester | Search human, mouse or rat genome for antigen 14-3-3 beta + zeta (Bioinformatic Harvester (EMBL)) |
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