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产品详细信息： 14-3-3 gamma (Human) antibody
14-3-3 gamma (Human) antibody
概述
| 抗原: | 14-3-3 gamma |
| 抗体类型: | 单克隆抗体 |
| 应用范围: | Immunoprecipitation (IP), Western Blotting (WB) |
| 目标物种: | Human |
| 抗体来源: | Mouse |
| 规格: | |
| 价格: | 256,00 € (加上运费和增值税) |
| 货号: | ABIN144249 |
| 发货时间: | 7 to 10 days until shipment |
详细信息: 14-3-3 gamma (Human) antibody
| 抗原 | 14-3-3 gamma |
| 免疫原 | Recombinant full length protein (Human 14-3-3 gamma). |
| 目标物种 | Human |
| 抗体类型 | 单克隆抗体 |
| 状态 | Liquid |
| 抗体同种型 | IgG1 »相配的二抗 |
| 描述 | Members of the 14-3-3 family of proteins are highly conserved proteins, localized in neurons, and are axonally transported to the nerve terminals. They are also present, at lower levels, in various other eukaryotic tissues. 14-3-3 proteins appear to play important roles in a variety of signal transduction pathways, including those involved in cell cycle regulation and cell survival. Because 14-3-3 proteins bind to specific phosphoserine containing sequences they are likely to have an important role in signaling pathways mediated by serine/threonine protein kinases. 14-3-3 proteins regulate many cellular processes that are important in cancer biology, such as apoptosis and cell cycle checkpoints. Evidence indicates 14-3-3 is required for Raf1 kinase activity and phosphorylation amoung many other functions. Levels of 14-3-3 gamma in the brain are significantly increased in Alzheimers disease and Down syndrome. |
| 克隆 | 3F8 |
| 抗体来源 | Mouse |
| 特异性 | No crossreactivity with other isoforms of 14-3-3. |
使用细节: 14-3-3 gamma (Human) antibody
| 应用范围 | Immunoprecipitation (IP), Western Blotting (WB) |
| 应用备注 | IP: Use at an assay dependent dilution. WB: Use at a concentration of 1-2 ug/ml. Predicted molecular weight: 30 kDa. Not tested in other applications. Optimal dilutions/concentrations should be determined by the end user. |
| 浓度 | 1 mg/ml |
| 纯度 | Protein G purified |
| 缓冲液 | Preservative: NoneConstituents: 10mM PBS |
| 研究领域 | Transcription Factors |
| 限制 | For research use only |
