BASKET
HELP
Product details for 5-Lipoxygenase (Phospho-Ser 523) antibody
5-Lipoxygenase (Phospho-Ser 523) antibody
Overview
| Antigen: | 5-Lipoxygenase (Phospho-Ser 523) |
| Antibody Type: | Polyclonal |
| Quantity: | |
| Price: | 359,00 € (Plus shipping costs and VAT) |
| Order number: | ABIN110308 |
| Availability: | 1 to 7 days before shipment |
Additional Information: 5-Lipoxygenase (Phospho-Ser 523) antibody
| Antigen | 5-Lipoxygenase (Phospho-Ser 523) |
| Antibody Type | Polyclonal |
| Description | The enzyme 5-lipoxygenase (5-LO) plays a key role in regulating the production of leukotrienes (LTs). Overproduction of LTs contributes to several diseases, most notably chronic inflammatory diseases such as asthma, fibrosis, and atherosclerosis. Recent work has demonstrated that the activity of 5-LO is regulated by protein kinase A (PKA) phosphorylation of serine-523 in 5-LO. Under normal conditions, this phosphorylation may be important in limiting inflammation. Abnormal signaling through cAMP and PKA, may therefore contribute to a variety of diseases, including those characterized by chronic inflammation. The phospho-specific antibody to Ser 523 on 5-LO provides a valuable tool for studying the role of 5-LO regulation in diseases such as asthma, fibrosis, and atherosclerosis. |
Application Details: 5-Lipoxygenase (Phospho-Ser 523) antibody
| Buffer | Affinity-purified rabbit polyclonal antibody |
| Storage | 1 year |
| Research Area | Enzymes |
| Restrictions | For Research only |
External Information: 5-Lipoxygenase (Phospho-Ser 523) antibody
| Google Scholar | Find more references for antigen 5-Lipoxygenase (Phospho-Ser 523) on Google Scholar™ |
| EMBL Harvester | Search human, mouse or rat genome for antigen 5-Lipoxygenase (Phospho-Ser 523) (Bioinformatic Harvester (EMBL)) |
browse antibodies by
Antigens
Secondary Antibodies
Research areas
Clones
Hosts
Applications
Reactivity
Supplier
Antigens
Secondary Antibodies
Research areas
Clones
Hosts
Applications
Reactivity
Supplier
