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Product details for APRIL (Human) antibody
APRIL (Human) antibody
Overview
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| Antigen: | APRIL |
| Antibody Type: | Monoclonal |
| Application: | Flow Cytometry (FACS), Western Blotting (WB) |
| Reactivity: | Human |
| Host: | Mouse |
| Quantity: | |
| Price: | 419,25 $ (Plus shipping costs and VAT, Invoice in EUR) |
| Order number: | ABIN144840 |
| Availability: | 7 to 10 days until shipment |
Additional Information: APRIL (Human) antibody
| Antigen | APRIL |
| Immunogen | Recombinant fragment, corresponding to amino acids 93-233 of Human APRIL, expressed in bacteria. |
| Reactivity | Human |
| Antibody Type | Monoclonal |
| Format | Liquid |
| Isotype | IgG1 »Matching secondary antibodies |
| Description | Members in the TNF superfamily regulate immune responses and induce apoptosis. A novel member in the TNF family was recently identified by several groups and designated APRIL (for A PRoliferation-Inducing Ligand), TALL2 (for TNF and ApoL-related Leukocyte-expressed Ligand 2), and TRDL 1a (for TNF related death ligand 1a) in human and mouse. Two receptors for APRIL were recently identified and designated TACI and BCMA. APRIL stimulates B and T cell proliferation, triggers humoral immune responses, activates NF-kB, and induces cell death. APRIL and its close relative of BlyS and their receptors BCMA and TACI are involved in diseases of autoimmunity and cancer. |
| Clone | Aprily-1 |
| Host | Mouse |
Application Details: APRIL (Human) antibody
| Application | Flow Cytometry (FACS), Western Blotting (WB) |
| Application Notes | FACS: Use at a concentration of 10 ug/ml. This antibody also works for intracellular FC staining. WB: Use at a concentration of 1 ug/ml. Predicted molecular weight: 30 kDa. Not tested in other applications. Optimal dilutions/concentrations should be determined by the end user. |
| Concentration | 1 mg/ml |
| Purity | >95% by SDS-PAGE |
| Buffer | Preservative: 0.02% Sodium AzideConstituents: PBS |
| Storage | Store at 4C. Aliquot and store at -20C long-term. |
| Research Area | Cell Cycle, Cytokines |
| Restrictions | For research use only |
External Information: APRIL (Human) antibody
| Google Scholar | Find more references for clone Aprily-1 on Google Scholar™ |
| EMBL Harvester | Search human, mouse or rat genome for antigen APRIL (Bioinformatic Harvester (EMBL)) |
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