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Product details for  APRIL (Human) antibody
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APRIL (Human) antibody

Overview

Antigen: APRIL
Antibody Type: Polyclonal
Application: Western Blotting (WB)
Reactivity: Human
Host: Rabbit
Quantity: 50 µg (0.5 mg/ml) (Product variants)
Price: 341,45 $   (Plus shipping costs and VAT, Invoice in EUR)
Order number: ABIN147909
Availability: 7 to 10 days until shipment
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Additional Information:  APRIL (Human) antibody

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Antigen APRIL
Immunogen Synthetic peptide, corresponding to amino acids 196-210 of Human APRIL.
Reactivity Human
Antibody Type Polyclonal
Format Liquid
Isotype IgG »Matching secondary antibodies
Description Members in the TNF superfamily regulate immune responses and induce apoptosis. A novel member in the TNF family was recently identified by several groups and designated APRIL (for a proliferation-inducing ligand), TALL 2 (for TNF- and ApoL-related Leukocyte-expressed Ligand 2), and TRDL-1a (for TNF related death ligand1a) in human and mouse. Two receptors for APRIL were recently identified and designated TACI and BCMA. APRIL stimulates B and T cell proliferation, triggers humoral immune responses, activates NF-kB, and induces cell death. APRIL and its close relative of BlyS and their receptors BCMA and TACI are involved in diseases of autoimmunity and cancer.
Host Rabbit

Application Details:  APRIL (Human) antibody

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Application Western Blotting (WB)
Application Notes WB: Use at a concentration of 2-4 ug/ml. Predicted molecular weight: 27 kDa. Can be blocked with GTX26094 APRIL peptide (human) Not tested in other applications. Optimal dilutions/concentrations should be determined by the end user.
Concentration 0.5 mg/ml
Purity Immunogen affinity purified
Buffer Preservative: 0.02% Sodium AzideConstituents: PBS
Storage Store at 2-8 C for up to one month. Aliquot and store at -20 C long term. Avoid repeated freeze / thaw cycles.
Research Area Cell Cycle, Cytokines
Restrictions For research use only

External Information:  APRIL (Human) antibody

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Google Scholar Find more references for antigen APRIL on Google Scholar™
EMBL Harvester Search human, mouse or rat genome for antigen APRIL (Bioinformatic Harvester (EMBL))