ARAP1 antibody (AA 1190-1450)
Quick Overview for ARAP1 antibody (AA 1190-1450) (ABIN238383)
Target
See all ARAP1 AntibodiesReactivity
Host
Clonality
Conjugate
Application
Clone
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Binding Specificity
- AA 1190-1450
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Specificity
- The antibody ARAP1-2 reacts with C-terminal part of ARAP1, a 160 kDa adaptor protein.
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Characteristics
- Synonyms: KIAA0782, Centaurin-delta-2, Arf-GAP, Rho-GAP domain, ANK repeat and PHdomain-containing protein 1
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Purification
- Protein A affinity chromatography
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Immunogen
- His6-tagged protein corresponding to amino acids 1190-1450 of human ARAP1
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Isotype
- IgG1
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anti-ArfGAP with RhoGAP Domain, Ankyrin Repeat and PH Domain 1 (ARAP1) (AA 1190-1450) antibody
ARAP1 Reactivity: Human WB, IP, ICC Host: Mouse Monoclonal ARAP1-2 unconjugated
anti-ArfGAP with RhoGAP Domain, Ankyrin Repeat and PH Domain 1 (ARAP1) (C-Term) antibodyVerified ARAP1 Reactivity: Human, Mouse ELISA, IHC, WB Host: Goat Polyclonal unconjugated
anti-ArfGAP with RhoGAP Domain, Ankyrin Repeat and PH Domain 1 (ARAP1) (AA 69-344) antibodyARAP1 Reactivity: Human ELISA, IHC, IF Host: Rabbit Polyclonal unconjugated
anti-ArfGAP with RhoGAP Domain, Ankyrin Repeat and PH Domain 1 (ARAP1) antibodyARAP1 Reactivity: Human, Mouse ELISA, IHC Host: Rabbit Polyclonal unconjugated
anti-ArfGAP with RhoGAP Domain, Ankyrin Repeat and PH Domain 1 (ARAP1) (C-Term) antibodyARAP1 Reactivity: Human WB Host: Rabbit Polyclonal unconjugated
anti-ArfGAP with RhoGAP Domain, Ankyrin Repeat and PH Domain 1 (ARAP1) (AA 834-1133) antibodyARAP1 Reactivity: Human WB, IF Host: Rabbit Polyclonal unconjugated
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Application Notes
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Suitable for Western Blotting (2 μg/mL). Immunoprecipitation. Immunocytochemistry.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
Restrictions
- For Research Use only
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Concentration
- 1.0 mg/mL
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Buffer
- PBS, pH 7.4 with 15 mM sodium azide as preservative.
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Preservative
- Sodium azide
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Precaution of Use
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- 4 °C/-20 °C
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Storage Comment
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Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer. Avoid freeze/thaw cycles.
Shelf life: One year from despatch. -
Expiry Date
- 12 months
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- ARAP1 (ArfGAP with RhoGAP Domain, Ankyrin Repeat and PH Domain 1 (ARAP1))
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Alternative Name
- ARAP1 / CENTD2
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Background
- ARAP1 (angiotensin II type 1 receptor-associated protein) is an adaptor protein with ArfGAP and RhoGAP activities, containing five PH domains and ankyrin repeate. This adaptor seems to serve as a link between phosphoinositide- Arf-, and Rho-mediated cell signaling. ARAP1 supports the plasma membrane recycling of angiotensin II type 1 receptor (AT1) and is important also for cell-specific trafficking of pro-death receptor TRAIL-R1 (DR4) to the plasma membrane, thus promoting the TRAIL-induced apoptosis in certain cell types. ARAP1 also affects cell spreading.Synonyms: ANK repeat and PH domain-containing protein 1, Arf-GAP, Centaurin-delta-2, KIAA0782, Rho-GAP domain
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Gene ID
- 116985
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UniProt
- Q96P48
Target
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