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Product details for Acetylcholine Receptor alpha (Human) antibody
Acetylcholine Receptor alpha (Human) antibody
Overview
| Antigen: | Neuronal (Nicotinic) Acetylcholine Receptor alpha chain |
| Antibody Type: | Monoclonal |
| Application: | Immunohistochemistry (Frozen Sections) (IHC (fro)), Flow Cytometry (FACS), Immunoprecipitation (IP), Western Blotting (WB) |
| Reactivity: | Human, Mouse (Murine) |
| Host: | Mouse |
| Quantity: | |
| Price: | 504,25 $ (Plus shipping costs and VAT, Invoice in EUR) |
| Order number: | ABIN119015 |
| Availability: | Ships in 3 to 10 days |
Additional Information: Acetylcholine Receptor alpha (Human) antibody
| Antigen | Neuronal (Nicotinic) Acetylcholine Receptor alpha chain |
| Immunogen | Human Acetylcholine Receptor |
| Reactivity | Human, Mouse (Murine) |
| Antibody Type | Monoclonal |
| Format | Ascites |
| Isotype | IgG1 »Matching secondary antibodies |
| Clone | G10 |
| Host | Mouse |
| Specificity | Human AchR-alpha subunit. Exhibits homogenous, high avidity binding to the receptor. A good Pan AchR marker as it binds well to normal, denervated and fetal AchR. Shows strong binding to endplate AchRs. Useful for studying the autoimmuneresponse in myasthenia gravis and the maturation of the human AchR during developement. Species crossreactivity: Mouse (strong) |
Application Details: Acetylcholine Receptor alpha (Human) antibody
| Application | Immunohistochemistry (Frozen Sections) (IHC (fro)), Flow Cytometry (FACS), Immunoprecipitation (IP), Western Blotting (WB) |
| Application Notes | Flow Cytometry (neat), immunohistochemistry on frozen sections (dilution 1:3), westernblot (dilution 1:100) and immunoprecipitation (dilution 1:100). Optimal dilutions should be determined by the user. |
| Buffer | This antibody is supplied as ascites in PBS containing 0.1 % sodium azide as preservative. |
| Storage | Store the antibody at 4-8°C for one month or at –20°C for longer. Do not use it beyond the expiration date stated on the label. |
| Research Area | Receptors |
| Restrictions | Research only |
Publications: Acetylcholine Receptor alpha (Human) antibody
| Publications |
Heidenreich, Vincent, Newsom-Davis: "Differences in fine specificity of anti-acetylcholine receptor antibodies between subgroups of spontaneous myasthenia gravis of recent onset, and of penicillamine induced myasthenia." In: Autoimmunity , Vol. 2, Issue 1, pp. 31-7, 1991/01 (PubMed) |
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