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Product details for Acetylcholinesterase (Bovine) antibody
Acetylcholinesterase (Bovine) antibody
Overview
| Antigen: | Acetylcholine Esterase |
| Antibody Type: | Monoclonal |
| Application: | Immunohistochemistry (Frozen Sections) (IHC (fro)), Enzyme Immunoassay (EIA), Immunoprecipitation (IP) |
| Reactivity: | Bovine, Cat (Feline), Guinea Pig, Human, Rabbit |
| Host: | Mouse |
| Quantity: | |
| Price: | 448,63 $ (Plus shipping costs and VAT, Invoice in EUR) |
| Order number: | ABIN121002 |
| Availability: | Ships in 3 to 10 days |
Additional Information: Acetylcholinesterase (Bovine) antibody
| Antigen | Acetylcholine Esterase |
| Immunogen | Purified human cerebellar acetylcholinesterase. |
| Reactivity | Bovine, Cat (Feline), Guinea Pig, Human, Rabbit |
| Antibody Type | Monoclonal |
| Format | Ascites |
| Isotype | IgG2b »Matching secondary antibodies |
| Clone | HR2 |
| Host | Mouse |
| Specificity | Cholinergic neurotransmission occurs in motor, autonomic and central nervous synapses and requires very rapid inactivation of its transmitter, acetylcholine (ACh). Acetylcholinesterase (AChE) rapidly hydrolyzes ACh to acetate and choline, thereby inactivating it. AChE is found in the neuromuscular junction anchored to the basal lamina which runs between the nerve terminal and muscle membrane. AChE is also found outside the nervous and neuromuscular system in blood, lymph, germ and liver cells suggesting a role for AChE not related to cholinergic transmission. Another less specific cholinesterase, butyrylcholinesterase (BChE), seems to contribute to the regulation of the ACh concentration in the synaptic cleft. This antibody detects acetylcholinesterase (AChE) from human, rabbit, guinea pig, bovine and cat tissues. This antibody does not detect butyrylcholinesterase (BChE), ABIN121002 has been successfully used in immunohistochemistry, immunoprecipitation and ELISA procedures. This antibody cannot be used in Western blot to detect AChE. Immunohistochemical staining of AChE in human brain samples with ABIN121002 results in staining of nerve fibers and terminals. ABIN121002 antigen is purified human cerebellar acetylcholinesterase. |
Application Details: Acetylcholinesterase (Bovine) antibody
| Application | Immunohistochemistry (Frozen Sections) (IHC (fro)), Enzyme Immunoassay (EIA), Immunoprecipitation (IP) |
| Application Notes | Immunohistochemistry on frozen sections: 1/50. Immunoprecipitation. ELISA. Other applications not tested. Optimal dilutions of this antibody are dependent on conditions and should be determined by the user. |
| Buffer | This antibody is supplied as liquid, PBS-diluted ascites containing 0.05% sodium azide as preservative. |
| Storage | Store the antibody at –20°C. Avoid repeated freezing and thawing. Shelf life: one year from despatch. |
| Research Area | Neurotransmitters |
| Restrictions | Research only |
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