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Product details for C-C Chemokine Receptor 7 (CCR7) (Human) antibody
C-C Chemokine Receptor 7 (CCR7) (Human) antibody
Overview
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| Antigen: | C-C Chemokine Receptor 7 (CCR7) |
| Antibody Type: | Polyclonal |
| Application: | Immunohistochemistry ((Frozen Sections) (IHC) (fro)), Immunohistochemistry (Formalin-fixed Sections) (IHC (f)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) |
| Reactivity: | Human |
| Host: | Rabbit |
| Quantity: | |
| Price: | 270,00 € (Plus shipping costs and VAT) |
| Order number: | ABIN141966 |
| Availability: | 7 to 10 days until shipment |
Additional Information: C-C Chemokine Receptor 7 (CCR7) (Human) antibody
| Antigen | C-C Chemokine Receptor 7 (CCR7) |
| Immunogen | Synthetic peptide-KLH conjugated |
| Reactivity | Human |
| Antibody Type | Polyclonal |
| Format | Liquid |
| Isotype | IgG »Matching secondary antibodies |
| Description | CCR7, a Chemokine Receptor, is involved in lymphocyte recirculation through secondary lymphoid organs and moving lymphocytes and dendritic cells into distinct tissue compartments. CCR7 is called the Epstein-Barr-induced receptor because it mediates Epstein-Barr viral effects on B lymphocytes. CCR7 expression is up-regulated in mature dendritic cells, B cells infected with EBV, and in CD4+ cells infected with human herpes virus 6 and 7. Immature dendritic cells have been shown to express chemokine receptor 5 (CCR5) and migrate in response to macrophage inflammatory protein-1alpha (MIP-1alpha), whereas mature dendritic cells switch to CCR7 expression and respond exclusively to MIP-3beta and 6Ckine. Maturing dendritic cells upregulate CCR7, which drives their migration to the T-cell areas of the draining lymph nodes where antigen is presented to naive T cells. CCR7 has been reported to be expressed in blood, bone marrow, lymph node, and intestine. This receptor is particularly expr |
| Host | Rabbit |
Application Details: C-C Chemokine Receptor 7 (CCR7) (Human) antibody
| Application | Immunohistochemistry ((Frozen Sections) (IHC) (fro)), Immunohistochemistry (Formalin-fixed Sections) (IHC (f)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) |
| Application Notes | Immunohistochemistry with formalin fixed paraffin embedded tissues. Not tested for other uses. IHC-P: Use at a dilution of 1/100-1/200. |
| Concentration | 1 mg/ml |
| Purity | Immunogen affinity purified. |
| Buffer | Phosphate buffered saline, PH 7.7 containing 0.01% sodium azide |
| Storage | Store at 4 C short term, For long term storage aliquot and store at -20 C or below. |
| Restrictions | For research use only |
External Information: C-C Chemokine Receptor 7 (CCR7) (Human) antibody
| Google Scholar | Find more references for antigen C-C Chemokine Receptor 7 (CCR7) on Google Scholar™ |
| EMBL Harvester | Search human, mouse or rat genome for antigen C-C Chemokine Receptor 7 (CCR7) (Bioinformatic Harvester (EMBL)) |
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