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Product details for CD47 (Human) antibody
CD47 (Human) antibody
Overview
| Antigen: | CD47 |
| Antibody Type: | Monoclonal |
| Application: | Flow Cytometry (FACS), Functional Studies (FUNC), Immunofluorescence (IF), Immunoprecipitation (IP) |
| Reactivity: | Human |
| Host: | Mouse |
| Quantity: | |
| Price: | 368,42 $ (Plus shipping costs and VAT, Invoice in EUR) |
| Order number: | ABIN145826 |
| Availability: | 7 to 10 days until shipment |
Additional Information: CD47 (Human) antibody
| Antigen | CD47 |
| Immunogen | Intact CD47 purified from placenta. |
| Reactivity | Human |
| Antibody Type | Monoclonal |
| Format | Liquid |
| Isotype | IgG1 »Matching secondary antibodies |
| Description | CD47 antigen, also known as integrin associated protein (IAP), is expressed on all hematopoietic cells, including leukocytes, platelets and erythrocytes. It is also expressed on epithelial cells, endothelial cells, fibroblasts and many tumor cell lines. CD47 may play a role as a signal transducer in the regulation of cation fluxes across cell membranes and in the chemotactic and adhesive interactions of leukocytes with endothelial cells. |
| Clone | B6H12-2 |
| Host | Mouse |
Application Details: CD47 (Human) antibody
| Application | Flow Cytometry (FACS), Functional Studies (FUNC), Immunofluorescence (IF), Immunoprecipitation (IP) |
| Application Notes | Flow Cytometry / Immunofluorescence (methanol fixed only) / Functional studies: assay dependent. Immunoprecipitation (native, with protein G): use at a concentration of 2ug / mg protein lysate. Not tested in other applications. Optimal dilutions / concentrations should be determined by the end user. This antibody blocks the binding of SIRP alpha (Yoshida, et al., Latour et al.) and inhibits in assays where CD47-integrin association is required. |
| Concentration | 1 mg/ml |
| Purity | Protein G purified |
| Buffer | 10mM PBS, pH7.4. Also available with BSA and sodium azide at 0.2 mg/ml as GTX72398 |
| Storage | Refrigerate at 4 C. Do not freeze. |
| Research Area | CD Antigens, Surface Receptors of Immune Cells |
| Restrictions | For research use only |
External Information: CD47 (Human) antibody
| Google Scholar | Find more references for clone B6H12-2 on Google Scholar™ |
| EMBL Harvester | Search human, mouse or rat genome for antigen CD47 (Bioinformatic Harvester (EMBL)) |
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