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产品详细信息： COX-2 (Human) antibody
COX-2 (Human) antibody
概述
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| 抗原: | COX-2 |
| 抗体类型: | 单克隆抗体 |
| 应用范围: | Immunohistochemistry (IHC), Western Blotting (WB), Immunoprecipitation (IP) |
| 目标物种: | Human |
| 抗体来源: | Mouse |
| 规格: | |
| 价格: | 315,00 € (加上运费和增值税) |
| 货号: | ABIN180049 |
| 发货时间: | 10 days until shipment |
详细信息: COX-2 (Human) antibody
| 抗原 | COX-2 |
| 免疫原 | Synthetic peptide for a part of Human COX-2 |
| 目标物种 | Human |
| 抗体类型 | 单克隆抗体 |
| 抗体同种型 | IgG1 »相配的二抗 |
| 描述 | Cyclooxygenase (COX) is a membrane bound enzyme responsible for the oxidation of arachidonic acid to Prostaglandin G2 (PGG2) and the subsequent reduction of PGG2 to PHG2. These reactions are the first steps in the formation of a variety of prostanoids. COX has been shown to be expressed in at least two different isoforms, a constitutively expressed form, COX-1, and an inducible form, COX-2. COX-1 is thought to regulate a number of housekeeping functions, such as vascular hemostasis, renal blood flow, and maintenance of glomerular function. Inflammation mediators such as growth factors, cytokines and endotoxin induce COX-2 expression in a number of cellular systems. |
| 克隆 | 13H14 |
| 抗体来源 | Mouse |
| 特异性 | Human COX-2 specific. No crossreactivities with Human COX-1. |
使用细节: COX-2 (Human) antibody
| 应用范围 | Immunohistochemistry (IHC), Western Blotting (WB), Immunoprecipitation (IP) |
| 应用备注 | This antibody can be stained in formalin fixed paraffin embedded tissues after microwave treatment by several Immunohistochemical techniques such as Avidin Biotin Complex (ABC) Method. The optimal dilution is 2-4 ug/ml, however, the dilution rate should be optimized by each laboratories. This antibody can be used for western blotting in concentration of 2-5 ug/ml. This antibody can be used for immunoprecipitation in concentration of 2-5 ug/ml. |
| 纯化 | Protein A |
| 缓冲液 | Lyophilized product from 1% BSA in PBS containing 0.05%NaN3 Reconstitution: 1 ml distilled water will be added to the product |
| 贮藏 | Lyophilized product, 5 years at 2 8 : Solution, 2 years at 20 |
| 研究领域 | Cancer |
| 限制 | For Research Use only |
