Product details for  Claudin-6 (C) (Mouse) antibody
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Claudin-6 (C) (Mouse) antibody

Overview

Image for Claudin-6 (C) (Mouse) antibody
Antigen: Claudin-6 (C)
Antibody Type: Polyclonal
Application: Immunohistochemistry (IHC), Western Blotting (WB)
Reactivity: Mouse (Murine)
Host: Rabbit
Quantity: 100 µg
Price: 315,00 €   (Plus shipping costs and VAT)
Order number: ABIN180218
Availability: 10 days until shipment

Additional Information:  Claudin-6 (C) (Mouse) antibody

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Antigen Claudin-6 (C)
Immunogen Synthetic peptide of part of C terminal of Mouse Claudin-6 (SRGPSEYPTKNYV) Purification: Purified with antigen peptide
Reactivity Mouse (Murine)
Antibody Type Polyclonal
Isotype IgG »Matching secondary antibodies
Description The tight junction is identified as a belt-like region in which two lipid-apposing membranes lie close together (tight junction strands). Tight junction strands of the adjacent cells form tightly connected pairs. The proteins involved in the formation of tight junctions are divided into two categories: 1) integral membrane proteins, such as occludin, claudin and junctional adhesion molecule, JAM and 2) peripheral membrane proteins (cytoplasmic plaque proteins), MAGUK (membrane-associated guanylate kinase) homologue proteins, such as ZO-1, 2, 3, cingulin, symplekin, 19B1, and AF-6. In human, the claudin superfamily consists of at least 18 members, which are involved on paracellular transport as structural and functional components of tight junction. Claudins are directly associated with ZO-1, 2 and 3 and indirectly with AF-6 and cingulin.
Host Rabbit
Specificity Claudin-6 specific. No crossreactivities with Claudin-1, -2, -3, -4, -5, -7, -8, -12, and -15 (This confirmed by western blotting using each transfectants)

Application Details:  Claudin-6 (C) (Mouse) antibody

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Application Immunohistochemistry (IHC), Western Blotting (WB)
Application Notes This antibody can be stained in frozen tissues by several Immunohistochemical techniques such as immunofluoroscent method. The optimal dilution is about 5 ug/mL, however, the dilution rate should be optimized by each laboratories.:This antibody can be used for western blotting in concentration of about 1ug/mL.
Purification Antigen peptide
Buffer Lyophilized product from 1% BSA in PBS containing 0.05% NaN3 . Reconstitution: 1.0 mL distilled water will be added to the product, then its concentration comes to 100 ug/mL
Storage Lyophilized product, 5 years at 2 ­ 8 C : Solution, 2 years at ­20 C
Restrictions For Research Use only

Images:  Claudin-6 (C) (Mouse) antibody

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F9Cell (HNF 4? induction)

Image for Claudin-6 (C) (Mouse) antibody (1)

F9 Cell (without induction)

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External Information:  Claudin-6 (C) (Mouse) antibody

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Google Scholar Find more references for antigen Claudin-6 (C) on Google Scholar™
EMBL Harvester Search human, mouse or rat genome for antigen Claudin-6 (C) (Bioinformatic Harvester (EMBL))