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Corticotropin-Releasing Factor Receptor 2 (CRHR2) (Human) antibody

Overview


	Antigen:	Corticotropin-Releasing Factor Receptor 2 (CRHR2)
	Antibody Type:	Polyclonal
	Application:	Immunohistochemistry ((Frozen Sections) (IHC) (fro)), Immunohistochemistry (Formalin-fixed Sections) (IHC (f)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
	Reactivity:	Human
	Host:	Rabbit
	Quantity:	25 µg (1 mg/ml) (Product variants)
	Price:	367,06 $ (Plus shipping costs and VAT, Invoice in EUR)
	Order number:	ABIN143450
	Availability:	7 to 10 days until shipment

Antigen	Corticotropin-Releasing Factor Receptor 2 (CRHR2)
Immunogen	Synthetic peptide-KLH conjugated
Reactivity	Human
Antibody Type	Polyclonal
Format	Liquid
Isotype	IgG »Matching secondary antibodies
Description	CRHR2, a Corticotropin-Releasing Factor Receptor is a neuroregulator of the hypothalamic-pituitary-adrenocortical axis and plays an important role in coordinating the endocrine, autonomic, and behavioral responses to stress and immune challenge. Mutations of the receptor reduce coping behaviors to stress and increase basal blood pressure. Three isoforms of CRHR2 are produced by alternative splicing. CRHR2 expression has been reported in various regions of the brain, as well as in placenta, umbilical vein, heart, epididymis, gastrointestinal tract, adrenal, and skeletal muscle. CRCH2alpha is the dominant isoform and is expressed widely. CRCH2beta is expressed in the hippocampus, septum, amygdala, heart, and skeletal muscle. CRHR2gamma is brain-specific. ESTs have been isolated from brain libraries.
Host	Rabbit

Application	Immunohistochemistry ((Frozen Sections) (IHC) (fro)), Immunohistochemistry (Formalin-fixed Sections) (IHC (f)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
Application Notes	Immunohistochemistry with formalin fixed paraffin embedded tissues. Not tested for other uses. IHC-P: Use at a dilution of 1/100-1/200.
Concentration	1 mg/ml
Purity	Immunogen affinity purified.
Buffer	Phosphate buffered saline, PH 7.7 containing 0.01% sodium azide
Storage	Store at 4 C short term, For long term storage aliquot and store at -20 C or below.
Restrictions	For research use only

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