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Product details for Cullin 1 (Human) antibody
Cullin 1 (Human) antibody
Overview
| Antigen: | Cullin 1 |
| Antibody Type: | Polyclonal |
| Application: | Immunohistochemistry ((Frozen Sections) (IHC) (fro)), Immunohistochemistry (Formalin-fixed Sections) (IHC (f)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunoprecipitation (IP), Western Blotting (WB) |
| Reactivity: | Human, Mouse (Murine) |
| Host: | Rabbit |
| Quantity: | |
| Price: | 426,88 $ (Plus shipping costs and VAT, Invoice in EUR) |
| Order number: | ABIN147724 |
| Availability: | 7 to 10 days until shipment |
Additional Information: Cullin 1 (Human) antibody
| Antigen | Cullin 1 |
| Immunogen | Synthetic peptide: C-DGEKDTYSYLA, corresponding to amino acids 742-752 of Human Cullin 1. |
| Reactivity | Human, Mouse (Murine) |
| Antibody Type | Polyclonal |
| Format | Liquid |
| Isotype | IgG »Matching secondary antibodies |
| Description | CUL 1 is a member of the family of human cullin genes (CUL 1, 2, 3, 4a, 4b, and 5) homologous to the S. cerevisiae cdc 53 gene. CUL 1 forms a complex with human p19 skp1 and F box protein p45 skp2, both of which, together with cdc 53 (known as CUL A), as three subunits form a ubiquitin ligase controlling proteolysis of G1 cell cycle regulatory proteins. The CUL 1/p19 skp1/p45 skp2complex is thought to play a role in the ubiquitination of G1 regulatory proteins. |
| Host | Rabbit |
Application Details: Cullin 1 (Human) antibody
| Application | Immunohistochemistry ((Frozen Sections) (IHC) (fro)), Immunohistochemistry (Formalin-fixed Sections) (IHC (f)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunoprecipitation (IP), Western Blotting (WB) |
| Application Notes | Immunoprecipitation (native): use at a concentration of 10ug / mg (protein A). Western Blotting: use at a concentration of 5-10ug / ml for 2hrs at RT. Immunohistochemistry (formalin fixed paraffin embedded): use at a concentration of 5-10ug / ml for 30 min at RT. Not tested in other applications. Optimal dilutions / concentrations should be determined by the end user. By Western blot, this antibody detects a band of 86 kDa, which corresponds to the predicted molecular weight of Cullin 1. No special pretreatment is required for immuno histochemical staining of formalin fixed tissues. |
| Concentration | 1 mg/ml |
| Purity | Protein A purified |
| Buffer | 10mM PBS, pH7.4, 0.2%BSA, 0.09% sodium azide |
| Storage | Refrigerate at 4 C. Do not freeze. |
| Research Area | Apoptosis/Necrosis, Proteasome |
| Restrictions | For research use only |
Product variants
| Cullin 1 (Human) antibody (Format: Liquid, Quantity: 7 ml) |
| Cullin 1 (Human) antibody (Quantity: 500 µl) |
External Information: Cullin 1 (Human) antibody
| Google Scholar | Find more references for antigen Cullin 1 on Google Scholar™ |
| EMBL Harvester | Search human, mouse or rat genome for antigen Cullin 1 (Bioinformatic Harvester (EMBL)) |
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