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Product details for Cullin 2 (Human) antibody
Cullin 2 (Human) antibody
Overview
| Antigen: | Cullin 2 |
| Antibody Type: | Polyclonal |
| Application: | Immunohistochemistry ((Frozen Sections) (IHC) (fro)), Immunohistochemistry (Formalin-fixed Sections) (IHC (f)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB) |
| Reactivity: | Human, Mouse (Murine) |
| Host: | Rabbit |
| Quantity: | |
| Price: | 426,88 $ (Plus shipping costs and VAT, Invoice in EUR) |
| Order number: | ABIN147295 |
| Availability: | 7 to 10 days until shipment |
Additional Information: Cullin 2 (Human) antibody
| Antigen | Cullin 2 |
| Immunogen | Synthetic peptide: C-RSQASADEYSYVA, corresponding to amino acids 733-745 of Human Cullin 2. |
| Reactivity | Human, Mouse (Murine) |
| Antibody Type | Polyclonal |
| Format | Liquid |
| Isotype | IgG »Matching secondary antibodies |
| Description | CUL 2 is a member of the family of human cullin genes (CUL 1, 2, 3, 4a, 4b, and 5), homologous to the S. cerevisiae cdc 53 gene. CUL 1 forms a complex with human p19 skp1 and F box protein p45 skp2. Together with cdc 53 (Known as Cul A), as three subunits, they form a ubiquitin ligase-controlling proteolysis of G1 cell cycle regulatory proteins. In contrast to CUL 1, CUL 2 does not associate with p19 skp1 and p45 skp2. Instead, CUL 2 forms a complex with an inactive transcriptional elongation complex, SIII, formed by three subunits: Elongain C, Elongin B and VHL. The function of this association remains unknown. |
| Host | Rabbit |
Application Details: Cullin 2 (Human) antibody
| Application | Immunohistochemistry ((Frozen Sections) (IHC) (fro)), Immunohistochemistry (Formalin-fixed Sections) (IHC (f)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB) |
| Application Notes | Western Blotting: use at a concentration of 5-10ug / ml for 2hrs at RT. Immunohistochemistry (formalin fixed paraffin embedded): use at a concentration of 5-10ug / ml for 30 min. Not tested in other applications. Optimal dilutions / concentrations should be determined by the end user. By Western blot, this antibody detects a band of 76 kDa, which corresponds to the predicted molecular weight of Cullin 2. No special pretreatment is required for immunohistochemical staining of formalin fixed tissues. |
| Concentration | 1 mg/ml |
| Purity | Protein A purified |
| Buffer | 10mM PBS, pH7.4, 0.2%BSA, 0.09% sodium azide |
| Storage | Refrigerate at 4 C. Do not freeze. : |
| Research Area | Apoptosis/Necrosis, Proteasome |
| Restrictions | For research use only |
Product variants
| Cullin 2 (Human) antibody (Format: Liquid, Quantity: 500 µl) |
| Cullin 2 (Human) antibody (Format: Liquid, Quantity: 7 ml) |
External Information: Cullin 2 (Human) antibody
| Google Scholar | Find more references for antigen Cullin 2 on Google Scholar™ |
| EMBL Harvester | Search human, mouse or rat genome for antigen Cullin 2 (Bioinformatic Harvester (EMBL)) |
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