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Product details for Cyclin D1 (Human) antibody
Cyclin D1 (Human) antibody
Overview
| Antigen: | Cyclin D1 |
| Antibody Type: | Monoclonal |
| Application: | Immunocytochemistry (ICC), Immunohistochemistry ((Frozen Sections) (IHC) (fro)), Immunohistochemistry (Formalin-fixed Sections) (IHC (f)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunoprecipitation (IP), Western Blotting (WB) |
| Reactivity: | Human, Mouse (Murine), Rat |
| Host: | Mouse |
| Quantity: | |
| Price: | 368,42 $ (Plus shipping costs and VAT, Invoice in EUR) |
| Order number: | ABIN144712 |
| Availability: | 7 to 10 days until shipment |
Additional Information: Cyclin D1 (Human) antibody
| Antigen | Cyclin D1 |
| Immunogen | Recombinant full length protein (Human). |
| Reactivity | Human, Mouse (Murine), Rat |
| Antibody Type | Monoclonal |
| Format | Liquid |
| Isotype | IgG2a »Matching secondary antibodies |
| Description | During each cell cycle cyclins undergo periodic accumulation and destruction. As key regulators of the cell cycle the cyclins control important transitions by activating Cdks. Early in the G1 phase of the cell cycle cyclin D1 induction is followed by cyclin E induction. This sequential progression is marked early on in G1 by the activation of Cdk4 and in mid to late G1 by the activation of Cdk2 and the hyperphosphorylation of pRB. The final transition into S phase is thought to be dependent on the increased expression and association of cyclin E and Cdk2. |
| Clone | DCS-6 |
| Host | Mouse |
| Specificity | Does not cross-react with other D-type cyclins. |
Application Details: Cyclin D1 (Human) antibody
| Application | Immunocytochemistry (ICC), Immunohistochemistry ((Frozen Sections) (IHC) (fro)), Immunohistochemistry (Formalin-fixed Sections) (IHC (f)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunoprecipitation (IP), Western Blotting (WB) |
| Application Notes | ICC: Use at an assay dependent dilution. IHC-P: Use at an assay dependent dilution. Perform heat mediated antigen retrieval via the microwave method before commencing with IHC staining protocol. IP: Use at an assay dependent dilution. WB: Use at a dilution of 1/200. Detects a band of approximately 36 kDa. Not tested in other applications. Optimal dilutions/concentrations should be determined by the end user. |
| Purity | Ascites |
| Buffer | Preservative: 15mM Sodium Azide |
| Research Area | Cell Cycle |
| Restrictions | For research use only |
External Information: Cyclin D1 (Human) antibody
| Google Scholar | Find more references for clone DCS-6 on Google Scholar™ |
| EMBL Harvester | Search human, mouse or rat genome for antigen Cyclin D1 (Bioinformatic Harvester (EMBL)) |
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