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Product details for Cyclin D1 (Human) antibody
Cyclin D1 (Human) antibody
Overview
| Antigen: | Cyclin D1 |
| Antibody Type: | Polyclonal |
| Application: | Immunohistochemistry ((Frozen Sections) (IHC) (fro)), Immunoprecipitation (IP), Western Blotting (WB) |
| Reactivity: | Human, Mouse (Murine), Rat |
| Host: | Rabbit |
| Quantity: | |
| Price: | 448,63 $ (Plus shipping costs and VAT, Invoice in EUR) |
| Order number: | ABIN146715 |
| Availability: | 7 to 10 days until shipment |
Additional Information: Cyclin D1 (Human) antibody
| Antigen | Cyclin D1 |
| Immunogen | Synthetic peptide (Human) (C terminal). |
| Reactivity | Human, Mouse (Murine), Rat |
| Antibody Type | Polyclonal |
| Isotype | IgG »Matching secondary antibodies |
| Description | During each cell cycle cyclins undergo periodic accumulation and destruction. As key regulators of the cell cycle the cyclins control important transitions by activating Cdks (1,2). Early in the G1 phase of the cell cycle cyclin D1 induction is followed by cyclin E induction (3,4). This sequential progression is marked early on in G1by the activation of Cdk4 and in mid to late G1 by the activation of Cdk2 and the hyperphosphorylation of pRB (3,5). The final transition into S phase is thought to be dependent on the increased expression and association of cyclin E and Cdk2 (5,6). |
| Host | Rabbit |
| Specificity | Reacts with cyclin D1 and weakly cross reactive with cyclin D2 |
Application Details: Cyclin D1 (Human) antibody
| Application | Immunohistochemistry ((Frozen Sections) (IHC) (fro)), Immunoprecipitation (IP), Western Blotting (WB) |
| Application Notes | IHC-Fr: Use at an assay dependent dilution. IP: Use at an assay dependent dilution. WB: Use at an assay dependent dilution. Predicted molecular weight: 38 kDa. Can be blocked with GTX27994 p38 (C-term) peptide (mouse) Not tested in other applications. Optimal dilutions/concentrations should be determined by the end user. |
| Concentration | 0.2 mg/ml |
| Purity | IgG fraction |
| Buffer | PBS with 0.1% sodium azide |
| Storage | Store this product at 4 C, do not freeze. The product is stable for one year from the date of shipment. |
| Research Area | Cell Cycle |
| Restrictions | For research use only |
Product variants
| Cyclin D1 (Human) antibody (Format: Liquid, Quantity: 7 ml) |
| Cyclin D1 (Human) antibody (Quantity: 100 µl) |
External Information: Cyclin D1 (Human) antibody
| Google Scholar | Find more references for antigen Cyclin D1 on Google Scholar™ |
| EMBL Harvester | Search human, mouse or rat genome for antigen Cyclin D1 (Bioinformatic Harvester (EMBL)) |
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