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Product details for Cyclin D1 (Human) antibody
Cyclin D1 (Human) antibody
Overview
| Antigen: | Cyclin D1 |
| Antibody Type: | Polyclonal |
| Application: | ELISA, Western Blotting (WB) |
| Reactivity: | Human, Mouse (Murine), Rat |
| Host: | Rabbit |
| Quantity: | |
| Price: | 545,16 $ (Plus shipping costs and VAT, Invoice in EUR) |
| Order number: | ABIN148860 |
| Availability: | 7 to 10 days until shipment |
Additional Information: Cyclin D1 (Human) antibody
| Antigen | Cyclin D1 |
| Immunogen | Full length fusion protein (human) |
| Reactivity | Human, Mouse (Murine), Rat |
| Antibody Type | Polyclonal |
| Isotype | IgG »Matching secondary antibodies |
| Description | During each cell cycle cyclins undergo periodic accumulation and destruction. As key regulators of the cell cycle the cyclins control important transitions by activating Cdks. Early in the G1 phase of the cell cycle cyclin D1 induction is followed by cyclin E induction. This sequential progression is marked early on in G1 by the activation of Cdk4 and in mid to late G1 by the activation of Cdk2 and the hyperphosphorylation of pRB. The final transition into S phase is thought to be dependent on the increased expression and association of cyclin E and Cdk2. |
| Host | Rabbit |
| Specificity | Antiserum will specifically react with a 35 kDa Cyclin D1 protein. No reaction was observed against other related cyclins. |
Application Details: Cyclin D1 (Human) antibody
| Application | ELISA, Western Blotting (WB) |
| Application Notes | Western blot-1:500 to 1:1000. A band at approximately 34kD corresponds to Cyclin D1. Higher MW bands might be seen corresponding to precipitating IgG. ELISA-1:500 to 1:2,000. Optimal titers for other applications should be determined by the researcher. |
| Concentration | 85 mg/ml |
| Purity | Whole antiserum |
| Buffer | Serum with 0.01% sodium azide |
| Storage | Store vial at -20 C or below prior to opening. Dilute only prior to immediate use. Aliquot contents and freeze at -20 C or below. Avoid cycles of freezing and thawing. |
| Research Area | Cell Cycle |
| Restrictions | For research use only |
Product variants
| Cyclin D1 (Human) antibody (Quantity: 1 ml) |
| Cyclin D1 (Human) antibody (Format: Liquid, Quantity: 7 ml) |
External Information: Cyclin D1 (Human) antibody
| Google Scholar | Find more references for antigen Cyclin D1 on Google Scholar™ |
| EMBL Harvester | Search human, mouse or rat genome for antigen Cyclin D1 (Bioinformatic Harvester (EMBL)) |
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